AB5666P

Anti-Neurite Outgrowth Inhibitor A/B/C Antibody

Chemicon^®, from rabbit

• 別名: Nogo-A/B/C
• UNSPSCコード: 12352203
• eCl@ss: 32160702

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 交差性: human, mouse, rat
• メーカー／製品名: Chemicon^®
• テクニック: ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: NM_007008.2; NM_020532.4; NM_153828.2; NM_207520.1; NM_207521.1
• UniProtアクセッション番号: Q9NQC3
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... RTN4(57142)

詳細

特異性

Recognizes human Neurite Outgrowth Inhibitor Protein A/B/C (Nogo-A/B/C). The immunogen peptide is within the 25 amino acid region identified for the inhibition of neurite outgrowth (Chen et al. 2000; GrandPre et al. 2000; Goldberg & Barres 2000; Prinijha et al. 2000; Tessier-Lavigne & Goodman 2000; Nagase et al. 1998).The immunogen shows no significant sequence homology with other known proteins.

SPECIES REACTIVITIES: The immunogen peptide is 92% conserved in rat Nogo or rat foocen-m1.2 protein (Chen et al. 2000; GrandPre et al. 2000; Goldberg & Barres 2000; Prinijha et al. 2000; Tessier-Lavigne & Goodman 2000; Nagase et al. 1998). Reactivity with other species has not been confirmed.

免疫原

A 13 amino acid peptide between the putative 2nd-3rd transmembrane domain of human Nogo-A (Chen et al. 2000; GrandPre et al. 2000; Goldberg & Barres 2000; Prinijha et al. 2000; Tessier-Lavigne & Goodman 2000; Nagase et al. 1998).

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
神経化学・ニューロトロフィン

成長円錐及び軸策ガイダンス

Anti-Neurite Outgrowth Inhibitor A/B/C Antibody is an antibody against Neurite Outgrowth Inhibitor A/B/C for use in ELISA & WB.

Western blot: 1-10 μg/mL using ECL. The calculated molecular weight of Nogo-A is approximately 135 kDa. However a molecular weight of approximately 180 kDa has been reported for full length Nogo-A (Chen et al. 2000; GrandPre et al. 2000; Goldberg & Barres 2000; Prinijha et al. 2000; Tessier-Lavigne & Goodman 2000; Nagase et al. 1998).



ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

Optimal working dilutions must be determined by the end user.

物理的形状

Liquid in PBS containing 0.1% BSA and 0.05% sodium azide.

保管および安定性

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids