AB5126

Anti-Melanocortin Receptor-1 Antibody

Chemicon^®, from rabbit

• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: affinity purified immunoglobulin
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 精製方法: affinity chromatography
• 化学種の反応性: mouse
• メーカー／製品名: Chemicon^®
• テクニック: ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: NM_002386.2
• UniProtアクセッション番号: Q01726
• 輸送温度: dry ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Mc1R(17199)

詳細

特異性

Melanocyte Stimulating Hormone Receptor (MSH-R), also called Melanotropin Receptor, or Melanocortin-1 Receptor (MC1-R), is a 315 aa transmembrane protein belonging to the family 1 of G-Protein coupled receptors. It is a receptor for MSH (a, b, g) and ACTH. Its activity is mediated by G-proteins that activate adenylate cyclase. It is found in Melanocytes and corticoadrenal tissue as well as various tissues like adrenal gland, leukocytes, lung, lymph node, ovary, testis, pituitary, placenta, spleen and uterus.

Mouse MSH-R. Reactivity with other species has not been confirmed. The immunogen sequence shows 70% homology with human, 66% with bovine, sheep and horse, and 60% with canine.

免疫原

A 21 mer peptide (designated MCR11) from the 3rd cytoplasmic domain of mouse MC1-R.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
CNSによる代謝制御

ホルモン及び受容体

Anti-Melanocortin Receptor-1 Antibody is an antibody against Melanocortin Receptor-1 for use in ELISA & WB.

Western blot: 1-10 μg/mL using Chemiluminescence technique

ELISA: 1:10,000 - 100,000



Optimal working dilutions must be determined by end user.

物理的形状

Affinity Purified immunoglobulin. Liquid in PBS, 0.1% BSA and 0.05% sodium azide.

保管および安定性

Can be refrigerated at 2-8°C in undiluted aliquots for short term use. Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable