AB15138

Anti-Nogo Receptor Antibody

from rabbit

• 別名: Reticulon-4 receptor, Nogo receptor, NgR, Nogo-66 receptor, Nogor, Rtn4r
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 化学種の反応性: mouse, human, rat
• テクニック: immunohistochemistry: suitable; western blot: suitable
• NCBIアクセッション番号: NM_022982
• UniProtアクセッション番号: Q99PI8
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: mouse ... Rtn4R(65079)

詳細

詳細

Axons are essential for neuronal communication but they do not regenerate after injury to the adult mammalian brain or spinal cord. Failed regeneration is due in part to the production of a potent axonal growth inhibitor, Nogo, by myelinating cells. The finding of a high affinity axonal receptor for the extracellular domain of Nogo provides the first insight into the basis of Nogo action. Disrupting the interaction of Nogo with the Nogo-66 receptor may facilitate axonal regeneration in vivo. The protein is dubbed the Nogo receptor because it binds with several other proteins that block neural growth. It is found to be ubiquitous in the brain and spinal cord.

特異性

Cat. # AB15138 recognizes the mature form of Nogo Receptor.

May react with human and primate based on sequence homology. Reactivity with other species has not been determined.

免疫原

Epitope: Mature Form

Recombinant protein.

アプリケーション

Research Category
ニューロサイエンス

Research Sub Category
成長円錐及び軸策ガイダンス

Anti-Nogo Receptor Antibody detects level of Nogo Receptor & has been published & validated for use in WB, IH.

Non-Lot Specific Tested Application 1:
Immunohistochemistry: Working dilutions of 1:50-1:500 in rat brain and spinal cord (paraffin embedded)

品質

Routinely tested on mouse cerebellum lysate.
Lot Specific Tested Application 1: Western Blot

ターゲットの説明

~50.9 kDa

物理的形状

Protein A purified

Format: Purified

Purified in PBS with 0.1% NaN3

保管および安定性

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

アナリシスノート

Control
Mouse cerebellum lysate

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable