AB15014

Anti-Glycine Receptor α3 subunit Antibody

Chemicon^®, from rabbit

• 別名: glycine receptor alpha 3 subunit, glycine receptor, alpha 3, glycine receptor, alpha-3 polypeptide, ligand gated ion channel
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 交差性: mouse, human
• メーカー／製品名: Chemicon^®
• テクニック: immunohistochemistry: suitable; western blot: suitable
• NCBIアクセッション番号: NP_006520.2
• UniProtアクセッション番号: O75311
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... GLRA3(8001)

詳細

詳細

Glycine receptor α3 subunit, also known as GLRA3, belongs to the ligand-gated ion channel family. Glycine functions as a inhibitory neurotransmitter throughout the CNS of mammals. The Glycine receptor is a neurotransmitter ligand-gated ion channel. GLRA3 is a pentamer that is composed of ligand binding alpha and structural beta subunits. When glycine binds to the receptor, chloride conductance increases which produces hyperpolarization. It is expressed in the hippocampus, olfactory bulb, and cerebellum. GLRA3 may be involved in human and murine neurological disorders.

特異性

Rat (92%) homology.

This antibody recognizes Glycine Receptor α3 subunit.

免疫原

This antibody is generated from rabbits immunized with a KLH conjugated linear peptide selected from residues surrounding the C-terminus of human Glycine Receptor α3 subunit.

アプリケーション

Anti-Glycine Receptor α3 subunit Antibody detects level of Glycine Receptor α3 subunit & has been published & validated for use in IH & WB.

Immunohistochemistry Analysis: 1:100-500 dilution from a previous lot detected Glycine Receptor α3 subunit in mouse spinal cord and mouse eye tissue.

ターゲットの説明

Approx. 48 kDa

物理的形状

Format: Purified

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 0.05% sodium azide.

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法的情報

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable