539508

PP2A₁, Bovine Kidney

• 別名: Protein Phosphatase 2A₁
• Enzyme Commission number: 3.1.3.16 (BRENDA, IUBMB)
• UNSPSCコード: 12352202

特性

• アッセイ: ≥90% (SDS-PAGE)
• 品質水準: 100
• フォーム: liquid
• 比活性: ≥750 units/mg protein
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

Native, PP2A₁ from bovine kidney. A divalent cation-independent protein serine/threonine phosphatase involved in the control of numerous cellular processes. Has a catalytic subunit of 36 kDa, a subunit of 55 kDa, and a regulatory subunit of 60 kDa. Reported to associate with microtubules and to bind to purified tubulin polymerized by TAXOL^® Drug.

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

単位の定義

One unit is defined as the amount of enzyme that will release 1.0 nmol of [³²P]P_i from ³²P-labeled phosphorylase per min at 30°C, pH 7.0.

物理的形状

In 50 mM Tris-HCl, 14 mM β-ME, 1 mM benzamidine, 1 mM EDTA, 100 µM PMSF, 50% glycerol, pH 7.0.

再構成

Following initial thaw, aliquot and freeze (-20°C).

その他情報

Hiraga, A. and Tamura, S. 2000. Biochem. J.346, 433.
Ferrigno, P., et al. 1993. Mol. Biol. Cell. 4, 669.
Guo, H. and Damuni, Z. 1993. Proc. Natl. Acad. Sci. USA90, 2500.
Hendrix, P., et al. 1993. J. Biol. Chem.268, 15267.
Amick, G.D., et al. 1992. Biochem. J. 287, 1019.
Cohen, P., et al. 1990. Trends Biochem. Sci.15, 98.
Damuni, Z., et al. 1989. J. Biol. Chem.264, 6412.1

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Taxol is a registered trademark of Bristol-Myers Squibb Co.

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable