528215

Anti-PAI-1 Mouse mAb (MA-33B8)

liquid, ≥90% (SDS-PAGE), clone MA-33B8

• 別名: Anti-Plasminogen Activator Inihibitor-1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: MA-33B8, monoclonal
• アッセイ: ≥90% (SDS-PAGE)
• フォーム: liquid
• 含まれません: preservative
• 化学種の反応性: rabbit, human
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; avoid repeated freeze/thaw cycles
• アイソタイプ: IgG
• 輸送温度: wet ice
• 保管温度: −70°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... SERPINE1(5054)

詳細

詳細

Purified mouse monoclonal antibody. Recognizes the ~50 kDa PAI-1 protein.

Recognizes the ~50 kDa PAI-1 protein.

This Anti-PAI-1 Mouse mAb (MA-33B8) is validated for use in Immunoblotting, Neutralization Studies for the detection of PAI-1.

免疫原

Human

human tPA-PAI-1 complex

アプリケーション

Immunoblotting (10 µg/ml)

Neutralization Studies (see application references)

包装

Please refer to vial label for lot-specific concentration.

警告

Toxicity: Standard Handling (A)

物理的形状

In 100 mM NaCl, 50 mM sodium phosphate buffer, pH 7.4.

再構成

Following initial thaw, aliquot and freeze (-20°C).

その他情報

Montes, R., et al. 2000. Thromb. Haemost.84, 65.
Verhamme, I., et al. 1999. J. Biol. Chem.274, 17511.
Debrock, S., and Declerck, P.J. 1997. Biochim. Biophys. Acta1337, 257.

Rapidly inactivates PAI-1 (Plasminogen Activator Inhibitor-1) to the latent form. Like the native latent form, PAI-1 inactivated by antibody was protected from cleavage by elastase. Also shown to reduce renal fibrin deposits in a rabbit model of endotoxemia. Variables associated with assay conditions will dictate the proper working dilution.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable