SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
Synonyms:
PAI, PAI-1, PAI1, PLANH1
Species:
Human SERPINE1 (5054), Mouse Serpine1 (18787), Rat Serpine1 (24617), cow SERPINE1 (281375), Zebrafish serpine1 (100136840), domestic guinea pig Serpine1 (100725387), naked mole-rat Serpine1 (101703903), Domestic Rabbit SERPINE1 (100009588), dog SERPINE1 (403476), domestic cat SERPINE1 (100127105)
UniProtKB ID:
Gene ID:
- Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
- Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
- Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
- domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
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ELISA
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PAI-1 (Ab-1) Mouse mAb (2), lyophilized, clone 2, Calbiochem®,
Species Reactivity
human
Application
Monoclonal Anti-SERPINE1 antibody produced in mouse, clone 1D5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry
immunohistochemistry
western blot
flow cytometry
immunohistochemistry
western blot
Anti-SerPINE1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rabbit, rat, sheep
Application
immunohistochemistry
western blot
western blot
Anti-SerPINE1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, rat, sheep
Application
western blot
Anti-SERPINE1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
Plasminogen activator inhibitor 1 (PAI-1) human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human