5.04359

Palmitoylethanolamide

• 別名: Palmitoylethanolamide, N-(2-Hydroxyethyl)hexadecanamide, PEA, Palmidrol
• 実験式（ヒル表記法）: C₁₈H₃₇NO₂
• CAS番号: 544-31-0
• 分子量: 299.49
• MDL番号: MFCD00020562
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• アッセイ: ≥99% (HPLC)
• 品質水準: 100
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; protect from light
• 色: white
• 溶解性: DMSO: 20 mM
• 保管温度: −20°C
• InChI: 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
• InChI Key: HXYVTAGFYLMHSO-UHFFFAOYSA-N

詳細

詳細

An endogenous lipid that acts as a selective agonist for GPR55 receptors (EC₅₀ = 4, 19 800 and >30 000 nM at GPR55, CB₂ and CB₁ receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC₅₀ = 3 µM).

生物化学的／生理学的作用

Primary Target
GPR55 receptor

警告

Toxicity: Standard Handling (A)

調製ノート

Slight warming is required for complete solubilization.

再構成

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

その他情報

Griffin, G., et al. 2000. J. Pharmacol. Exp. Ther.292, 886.

Lambert, D., et al. 2001. Epilepsia.42, 321.
Lambert, D., et al. 2002. Curr. Med. Chem.9, 663.
Lo Verme, J., et al. 2005. Life Sci.77, 1685.
Re, G., et al. 2005. Vet. J.173, 21.
Ryberg, R., et al. 2007. Br. J. Pharmacol.152, 1092.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS05,GHS09
• シグナルワード: Danger
• 危険有害性情報: H315 - H318 - H411
• 注意書き: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• 危険有害性の分類: Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable