487950

NOC-5

A nitric oxide (NO) donor.

• 別名: NOC-5, 3-[2-Hydroxy-1-(1-methylethyl)-2-nitrosohydrazino]-1-propanamine
• 実験式（ヒル表記法）: C₆H₁₆N₄O₂
• CAS番号: 146724-82-5
• 分子量: 176.22
• MDL番号: MFCD00274389
• UNSPSCコード: 12352200

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated (hygroscopic); protect from light
• 色: white
• 溶解性: 0.1 M NaOH: soluble; water: soluble
• 輸送温度: ambient
• 保管温度: −20°C
• InChI: 1S/C6H16N4O2/c1-6(2)9(5-3-4-7)10(12)8-11/h6,12H,3-5,7H2,1-2H3
• InChI Key: WEHZRCACNLQADC-UHFFFAOYSA-N

詳細

詳細

A nitric oxide (NO) donor. A stable NO-amine complex that can release two equivalents of NO spontaneously in solution under physiological conditions without a cofactor. Half-life (t_½) of NO release is 93 min (PBS, pH 7.4, 22°C).

A nitric oxide (NO) donor. A stable NO-amine complex that can spontaneously release two equivalents of NO in solution under physiological conditions without any cofactor. Half-life (t_½) in PBS, pH 7.4 is 93 minutes at 22°C. Relatively stable in alkaline solution (pH ≥10.0).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
A nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Irritant (B)

再構成

Following reconstitution in alkaline solution, aliquot and freeze (-20°C). Unstable in aqueous solutions; reconstitute in H₂O just prior to use. Alkaline stock solutions are stable for up to 3 months at -20°C.

その他情報

Hrabie, J.A., et al. 1993. J. Org. Chem. 58, 1472.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02
• シグナルワード: Danger
• 危険有害性情報: H242
• 注意書き: P210 - P234 - P235 - P240 - P370 + P378 - P403
• 危険有害性の分類: Self-react. C
• 保管分類コード: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable