219399

Cathepsin D Substrate I

Useful as a substrate for the determination of cathepsin D activity.

• 別名: Cathepsin D Substrate I, Bz-RGFFP-4-MeOβNA, HCl
• 実験式（ヒル表記法）: C₄₉H₅₅N₉O₇ · xHCl
• 分子量: 882.02 (free base basis)
• UNSPSCコード: 51111800
• NACRES: NA.77

特性

• 品質水準: 100
• アッセイ: ≥95% (HPLC)
• 形状: lyophilized solid
• メーカー／製品名: Calbiochem^®
• 保管条件: OK to freeze; desiccated; protect from light
• 色: white
• 溶解性: DMSO: 5 mg/mL
• 蛍光検出: λ_ex ~345 nm; λ_em ~425 nm
• 輸送温度: ambient
• 保管温度: −20°C

詳細

詳細

A useful substrate for colorimetric or fluorometric assay of cathepsin D activity. Cathepsin D hydrolyzes the Phe-Phe bond. Dipeptidyl aminopeptidase II is required to free the 4-methoxy-β-naphthylamine (4MβNA). Excitation max: ~345 nm; emission max: ~425 nm.

Useful as a substrate for the determination of cathepsin D activity. Suitable for either colorimetric or fluorometric assay. Cathepsin D hydrolyzes the Phe-Phe bond. Requires dipeptidyl aminopeptidase II to free 4-methoxy-β-naphthylamine (4MeOβNA).

生物化学的／生理学的作用

Cell permeable: no

Primary Target
Substrate for the determination of cathepsin D activity

Product does not compete with ATP.

Reversible: no

警告

Toxicity: Standard Handling (A)

シーケンス

Bz-Arg-Gly-Phe-Phe-Pro-4MeOβNA, HCl

その他情報

Takahashi, T., and Tang, J. 1981. Methods Enzymol.80, 565.
Smith, R.E., and Van Frank, R.M. 1975. in Lysosomes in Biology and Pathology4 (Dingle, J.T., and Dean, R.T., eds.) p. 193, American Elsevier, Holland.

法的情報

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable