1.08178

トリフルオロ酢酸

for protein sequence analysis

• 別名: TFA
• 化学式: CF₃COOH
• CAS番号: 76-05-1
• 分子量: 114.02
• Beilstein: 742035
• MDL番号: MFCD00004169
• UNSPSCコード: 12352106
• EC Index Number: 200-929-3
• NACRES: NA.21

特性

• 蒸気密度: 3.9 (vs air)
• 品質水準: 200
• 蒸気圧: 97.5 mmHg ( 20 °C)
• アッセイ: ≥99.7% (acidimetric)
• 形状: liquid
• 不純物: ≤0.02% Water (Karl Fischer)
• 屈折率: n20/D 1.3 (lit.)
• pH: 1 (10 g/L in H₂O)
• bp: 72.4 °C (lit.)
• mp: −15.4 °C (lit.)
• 溶解性: soluble 10 g/mL
• 密度: 1.489 g/mL at 20 °C (lit.)
• 保管温度: 2-30°C
• SMILES記法: OC(C(F)(F)F)=O
• InChI: 1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)
• InChI Key: DTQVDTLACAAQTR-UHFFFAOYSA-N

詳細

アプリケーション

Trifluoroacetic acid (TFA) can be used as an ion-pairing agent in a reverse-phase HPLC system to separate peptides because it enhances peak resolution. It also has low absorption detection wavelengths and is relatively volatile and can be easily removed. For the majority of peptide separations, TFA has been used at concentrations ranging from 0.05 to 0.1%(6.5-13 mM).

アナリシスノート

Assay (acidimetric): ≥ 99.7 %
Identity (IR-spectrum): passes test
Density (d 20 °C/20 °C): about 1.53
Boiling point: about 72 °C
Water (according to Karl Fischer): ≤ 0.02 %

安全性情報

• ピクトグラム: GHS05,GHS07
• シグナルワード: Danger
• 危険有害性情報: H314 - H332 - H412
• 注意書き: P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• 危険有害性の分類: Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A
• 保管分類コード: 8A - Combustible, corrosive hazardous materials
• WGK: WGK 2
• 引火点(°F): 212.0 °F - Pensky-Martens closed cup
• 引火点(℃): > 100 °C - Pensky-Martens closed cup