1.06143

N-メチル-D-グルカミン

low in endotoxins, EMPROVE^® API, Ph. Eur., ChP, JP, USP

• 別名: 1-デオキシ-1-（メチルアミノ）-D-グルシトール, メグルミン
• 実験式（ヒル表記法）: C₇H₁₇NO₅
• CAS番号: 6284-40-8
• 分子量: 195.21
• Beilstein: 385906
• MDL番号: MFCD00004707
• UNSPSCコード: 12352104
• EC Index Number: 228-506-9

特性

• 認証: ChP; JP; Ph. Eur.; USP
• 品質水準: 600
• 製品種目: EMPROVE^® API
• 形状: extra fine powder; solid
• 自己発火温度: ~662 °F
• 有効性: >5000 mg/kg LD₅₀, oral (Rat)
• テクニック: API processing | salt formation: suitable
• pH: 11 (20 °C, 10 g/L in H₂O)
• bp: 210 °C/1013 hPa (decomposes)
• mp: 129-131.5 °C (lit.)
• アプリケーション: liquid formulation; parenterals; pharma/biopharma processes; pharmaceutical; solid formulation; solubility enhancement
• 保管温度: no temp limit
• SMILES記法: CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
• InChI: 1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
• InChI Key: MBBZMMPHUWSWHV-BDVNFPICSA-N

詳細

詳細

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

アプリケーション

Meglumine API grade is a high-quality advanced intermediate that can be directly incorporated as a co-former in API formulations.
Meglumine Emprove^® API is manufactured according to ICH Q7 guidelines.

法的情報

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• 保管分類コード: 11 - Combustible Solids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable