07-1491

Anti-Calcineurin pan A Antibody

from rabbit, purified by affinity chromatography

• 別名: CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, calcineurin A alpha, protein phosphatase 3 (formerly 2B), catalytic subunit, ; ; alpha isoform, protein phosphatase 3 (formerly 2B), catalytic subunit, ; ; alp
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100; 200
• 結合体: conjugate
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: liquid
• 精製方法: affinity chromatography
• 化学種の反応性: human, rat, mouse
• 化学種の反応性（ホモロジーによる予測）: mammals (based on 100% sequence homology)
• テクニック: western blot: suitable
• 免疫原配列: KLH-conjugated synthetic peptide corresponding to Calcineurin.
• NCBIアクセッション番号: NP_000935.1
• UniProtアクセッション番号: Q08209
• 輸送温度: wet ice
• 保管温度: −20°C

詳細

詳細

Calcineurin is a serine/threonine protein phosphatase involved in the mediation of signal tranduction in a wide variety of cellular responses. Calcineurin has been linked to Pmk1 MAP kinase and PI pathways, as well as to members of the small GTPase Rab/Ypt family and Type II myosin. Furthermore, calcineurin participates in the transduction of extracellular signals to the nucleus by dephosphorylation of members of the NFAT family of transcription factors. These linkages demonstrate calcineurin′s multifunctional capabilities in the regulation of calcium signaling.

特異性

This antibody recognizes both the Aα and Aβ, the major catalytic subunit gene isoforms of calcineurin in most tissues; may also react with the testis form, Aγ. This antibody has very high sensitivity and specificity, which allow detection of calcineurin in tissues where expression is low, such as lymphoid tissue. Reacts with calcineurin of all mammalian species.

免疫原

KLH-conjugated synthetic peptide corresponding to Calcineurin.

アプリケーション

Research Category
細胞シグナル伝達

Research Sub Category
GPCR、cAMP/cGMP及びカルシウムシグナル伝達

Detect Calcineurin pan A using this Anti-Calcineurin pan A Antibody validated for use in WB.

品質

Evaluated by Western Blot in Mouse brain lysate.
Western Blot Analysis: 1:1,000 dilution of this antibody detected Calcineurin on 10 µg of mouse brain lysate.

ターゲットの説明

~58 kDa

関連事項

Replaces: AB1695

物理的形状

Affinity purified

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH7.4) 150 mM NaCl with 40% gylerol. Contains no preservative.

保管および安定性

Store at -20°C for up to 12 months in undiluted aliquots; at this temperature the solution will
remain unfrozen.

アナリシスノート

Control
Mouse brain lysate

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable