06-018

Anti-ROR2 Antibody, CT

from rabbit

• 別名: Neurotrophic tyrosine kinase, receptor-related 2, neurotrophic tyrosine kinase receptor-related 2, receptor tyrosine kinase-like orphan receptor 2, tyrosine-protein kinase transmembrane receptor ROR2
• UNSPSCコード: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

特性

• 由来生物: rabbit
• 抗体製品の状態: purified antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 交差性: human
• テクニック: immunohistochemistry: suitable (paraffin)
• NCBIアクセッション番号: NP_004551.2
• UniProtアクセッション番号: Q01974
• 輸送温度: wet ice
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ROR2(4920)

詳細

詳細

Receptor tyrosine kinase-like orphan receptor 2, also known as ROR2, is a member of the Tyr protein kinase family and ROR subfamily of cell surface receptors. Located in the transmembrane, ROR2 is highly expressed during early embryonic development and is associated with chondrocyte formation, cartilage and growth plate maturity. Expression levels of ROR2 subside after 16 days and occur minimally in adults. ROR2 is post translationaly modified by ATM or ATR phosphorylation when DNA damage occurs. Mutations in ROR2 result in brachydactyly type B1 (BDB1), characterized by either hypoplasia or aplasia of the distal phalanges and nails. ROR2 is also associated with recessive Robinow syndrome (RRS), resulting in shortening of limbs, facial dysmorphia and spinal defects.

特異性

This antibody recognizes the C-terminal region of ROR2.

免疫原

Epitope: C-terminus

KLH-conjugated synthetic linear peptide corresponding to the C-terminal region of ROR2

アプリケーション

Research Category
炎症及び免疫

Research Sub Category
免疫シグナル伝達

Anti-ROR2 Antibody, C-terminus detects level of ROR2 & has been published & validated for use in IH(P).

品質

Evaluated by immunohistochemistry (paraffin) in human gastric mucosa.

Immunohistochemistry(paraffin): 1:50-1:200 dilution of this antibody detected ROR2 in human gastric mucosa.

ターゲットの説明

~105 kDa

物理的形状

Protein G Purified

Format: Purified

Purified rabbit polyclonal in buffer containing PBS and 0.09% sodium azide.

保管および安定性

Stable for 1 year at 2-8ºC from date of receipt.

アナリシスノート

Control
Human gastric mucosa

その他情報

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable