Full-length human origin recognition complex 2 (ORC2). Clone 3G6.
アプリケーション
Research Category エピジェネティクス及び核内機能分子
Research Sub Category 細胞周期、DNA複製及び修復
Detect ORC2 with Anti-ORC2 Antibody, clone 3G6 (Rat Monoclonal Antibody), that has been shown to work in IP & WB.
品質
Routinely evaluated by immunoblot.
ターゲットの説明
65-70kDa
物理的形状
Protein G Purified
Format: Purified
保管および安定性
2 years at -20°C from date of shipment
アナリシスノート
Control Positive Antigen Control: Catalog #12-309, Hela cell nuclear extract. Add an equal volume of Laemmli reducing sample buffer to 10 μL of extract and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced extract per lane for minigels.
法的情報
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
DNA-damage signaling utilizes a multitude of posttranslational modifiers as molecular switches to regulate cell-cycle checkpoints, DNA repair, cellular senescence, and apoptosis. Here we show that RNF8, a FHA/RING domain-containing protein, plays a critical role in the early DNA-damage response. We