N-005

Norcodeine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 実験式（ヒル表記法）: C₁₇H₁₉NO₃
• CAS番号: 467-15-2
• 分子量: 285.34
• EC Number: 200-659-6
• MDL番号: MFCD00069317
• UNSPSCコード: 41116107
• PubChem Substance ID: 329818393
• NACRES: NA.24

特性

• グレード: certified reference material
• 品質水準: 300
• 形状: liquid
• 特徴: Snap-N-Spike^®/Snap-N-Shoot^®
• 包装: ampule of 1 mL
• メーカー／製品名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 1.0 mg/mL in methanol
• テクニック: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• アプリケーション: forensics and toxicology
• フォーマット: single component solution
• 保管温度: −20°C
• SMILES記法: COc1ccc2C[C@H]3NCC[C@@]45[C@@H](Oc1c24)[C@@H](O)C=C[C@@H]35
• InChI: 1S/C17H19NO3/c1-20-13-5-2-9-8-11-10-3-4-12(19)16-17(10,6-7-18-11)14(9)15(13)21-16/h2-5,10-12,16,18-19H,6-8H2,1H3/t10-,11+,12-,16-,17-/m0/s1
• InChI Key: HKOIXWVRNLGFOR-KOFBORESSA-N

詳細

詳細

Norcodeine is a primary urinary metabolite of codeine. Codeine is an opiate used for its analgesic, antitussive, and sedative properties and is the second-most predominant alkaloid in opium. This certified Snap-N-Spike^® Solution is applicable for use in LC/MS or GC/MS applications from urine drug testing and pain prescription monitoring to clinical toxicology and forensic analysis.

アプリケーション

• Pharmacokinetics and nociceptive effects of codeine in horses: A study conducted by Knych HK et al., investigated the pharmacokinetics and the effects on thermal nociception in horses following the administration of codeine. This research provides valuable data for understanding how opioid metabolites like norcodeine behave in non-human subjects, aiding in veterinary pharmacological applications (Knych et al., 2022).
• Opioid metabolite analysis in forensic toxicology: Jakobsson G and colleagues developed a method using LC-MS/MS to analyze heroin-related compounds, including norcodeine, in postmortem samples. This research is crucial for forensic investigations, providing detailed insights into the metabolite profiles that can assist in the detection and analysis of opioid abuse cases (Jakobsson et al., 2021).
• Analysis of opioid metabolites in forensic cases: Feliu C et al. presented a technique for quantifying various opioids and their derivatives, such as norcodeine, in whole blood using liquid chromatography-high-resolution mass spectrometry. This method is significant for forensic science, contributing to the accurate assessment of substances involved in fatal cases (Feliu et al., 2020).

法的情報

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全性情報

• ピクトグラム: GHS02,GHS06,GHS08
• シグナルワード: Danger
• 危険有害性情報: H225,H301 + H311 + H331,H370
• 注意書き: P210 - P260 - P280 - P301 + P310 - P311
• 危険有害性の分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 保管分類コード: 3 - Flammable liquids
• WGK: WGK 1
• 引火点(°F): 49.5 °F - closed cup
• 引火点(℃): 9.7 °C - closed cup