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資料

安全性情報

860042P

Avanti

16:0-d31-18:1 PI

1-palmitoyl-d31-2-oleoyl-sn-glycero-3-phosphoinositol (ammonium salt), powder

別名:

110923

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About This Item

実験式（ヒル表記法）:
C43H53NO13PD31
CAS番号:
799812-61-6
分子量:
885.29
UNSPSCコード:
51191904
NACRES:
NA.25

アッセイ

>99% (TLC)

形状

powder

包装

pkg of 1 × 100 μg (with stopper and crimp cap (860042P-100ug))
pkg of 1 × 500 μg (with stopper and crimp cap (860042P-500ug))

メーカー／製品名

Avanti Research™ - A Croda Brand 860042P

輸送温度

dry ice

保管温度

−20°C

SMILES記法

[NH4+].[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C(=O)OC[C@H](COP([O-])(=O)O[C@H]1C(O)C(O)C(O)[C@@H](O)C1O)OC(=O)CCCCCCC\C=C/CCCCCCCC

詳細

16:0-d31-18:1 PI or 1-palmitoyl-d31-2-oleoyl-sn-glycero-3-phosphoinositol is a deuterated phospholipid. This lipid consists of a phosphatidylinositol group attached to palmitic acid and oleic acid.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

アプリケーション

16:0-d31-18:1 PI or 1-palmitoyl-d31-2-oleoyl-sn-glycero-3-phosphoinositol has been used as an internal standard:
  • in yeast lipid profiling
  • for the quantification of lipids using electrospray ionization tandem mass spectrometry (ESI-MS/MS)
  • for the extraction of lipids from human bronchus tissue and epithelium samples using Bligh and Dyer method and for liquid chromatography-mass spectrometry (LC-MS) analysis

生物化学的／生理学的作用

Phosphatidylinositol (PI) is phosphorylated at their hydroxyls group and the phosphorylated PIs regulate several biological processes including membrane trafficking, recruitment of proteins and autophagy.

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (860042P-100ug)
2 mL Amber Serum Vial with Stopper and Crimp Cap (860042P-500ug)

法的情報

Avanti Research is a trademark of Avanti Polar Lipids, LLC

保管分類コード

11 - Combustible Solids

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

860042P-VAR:
860042P-BULK:
860042P-100UG:
860042P-500UG:

試験成績書（COA）

製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Nicholas J Blunsom et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1865(1), 158471-158471 (2019-06-08)
Phosphatidylinositol (PI) is a minor phospholipid with a characteristic fatty acid profile; it is highly enriched in stearic acid at the sn-1 position and arachidonic acid at the sn-2 position. PI is phosphorylated into seven specific derivatives, and individual species
Nicole Zehethofer et al.
Chromatographia, 78(5-6), 403-413 (2015-03-10)
Airway epithelial cells play an important role in the pathogenesis of inflammatory lung diseases such as asthma, cystic fibrosis and COPD. Studies concerning the function of the lipid metabolism of the airway epithelium are so far based only on the
G van Echten-Deckert et al.
The Journal of biological chemistry, 272(25), 15825-15833 (1997-06-20)
The effect of six different structurally modified sphingosine analogues on biosynthesis of sphingolipids was studied in primary cultured murine cerebellar neurons. Treatment of cells with cis-4-methylsphingosine at micromolar levels resulted in a markedly decreased sphingolipid biosynthesis, whereas the other compounds
Michael Ter Braak et al.
Biochemical pharmacology, 81(5), 617-625 (2010-12-18)
Sphingosine-1-phosphate (S1P) acts as high affinity agonist at specific G-protein-coupled receptors, S1P(1-5), that play important roles e.g. in the cardiovascular and immune systems. A S1P receptor modulating drug, FTY720 (fingolimod), has been effective in phase III clinical trials for multiple
Michael Maceyka et al.
Trends in cell biology, 22(1), 50-60 (2011-10-18)
The bioactive sphingolipid metabolite sphingosine-1-phosphate (S1P) is now recognized as a critical regulator of many physiological and pathophysiological processes, including cancer, atherosclerosis, diabetes and osteoporosis. S1P is produced in cells by two sphingosine kinase isoenzymes, SphK1 and SphK2. Many cells
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