フォーム
liquid
メーカー／製品名
Avanti Research™ - A Croda Brand
包装
1 ea of 1 × (ELISA strip packaged in foil pouch)
輸送温度
wet ice
保管温度
2-8°C
詳細
Avanti Lipid Snoopers™ are lipid microarrays useful in semi-quantitative measurements. These snoopers are relatively stable and provide a higher sensitivity compared to the conventional enzyme-linked immunosorbent assays (ELISA) methods.[1] Ceramide-1-Phosphate (Cer1P) is a bioactive anionic sphingolipid.[2] Ceramide kinase (CERK) mediates the synthesis of Cer1P.[3] Cer1P is also synthesized by the hydrolysis of sphingomyelin in the presence of enzyme sphingomyelinase (SMase).[4]
ELISA Snoopers™ are 8-well strips pre-coated with a single high-quality lipid species. They can be used to investigate protein-lipid interactions, and characterize and titrate lipid binding proteins. This format provides the following advantages:
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
- quantitative lipid-protein binding studies
- assemble a 96-well plate using only the lipids of interest for binding studies
- flexibility - use 8 to 96 wells, and 1 to 12 lipids as needed.
The 8-well strips are available in optically clear, white, or black surfaces for use in colormetric, luminescent and fluorescent assays, respectively. Avanti Lipid Snoopers ELISA Strips allow multiple sample conditions to be probed simultaneously in a single plate making them a perfect complement to Avanti Lipid Snoopers Nitrocellulose Strips.
生物化学的／生理学的作用
Ceramide-1-Phosphate (Cer1P) mediates macrophage migration, regulates autocrine and paracrine mediators.[2] Elevated levels of Cer1P leads to negative regulation of ceramide kinase (CERK). The intracellular calcium levels modulate Cer1P and CERK functionality.[3] Cer1P is also a crucial regulator of phagocytosis, inflammation, apoptosis and mitosis.[5] Avanti Lipid Snoopers™ have been used successfully in elucidating the role of annexin V in membrane trafficking.[1]
包装
ELISA Strip Packaged in Foil Pouch (330687-1EA)
法的情報
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Snoopers is a trademark of Avanti Polar Lipids, LLC
保管分類コード
10 - Combustible liquids
WGK
WGK 3
引火点(°F)
No data available
引火点(℃)
No data available
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
330687-1EA:
330687-VAR:
最新バージョンのいずれかを選択してください：
A Nonradioactive Fluorimetric SPE-Based Ceramide Kinase Assay Using NBD-C6-Ceramide
Van O, et al.
Journal of Lipids, 2012 (2012)
Ceramide-1-phosphate, a new bioactive sphingolipid in regulating cell signaling
Marcu AC and Chalfant CE
Future Lipidology , 2(1), 75-84 (2007)
Regulation of the amount of ceramide-1-phosphate synthesized in differentiated human podocytes
Mallela SK, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1864(12), 158517-158517 (2019)
Ceramide 1-phosphate mediates endothelial cell invasion via the annexin a2-p11 heterotetrameric protein complex
Hankins JL, et al.
Test, 288(27), 19726-19738 (2013)
Avanti lipid tools: connecting lipids, technology, and cell biology
Sims KH, et al.
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1841(8), 1038-1048 (2014)
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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