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Merck

803596

Sigma-Aldrich

BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)

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About This Item

実験式(ヒル表記法):
C16H20N2O7
分子量:
352.34
MDL番号:
UNSPSCコード:
12352200
PubChem Substance ID:
NACRES:
NA.22

アッセイ

≥90%

形状

powder

分子量

352.34

反応適合性

reagent type: cross-linking reagent

保管条件

desiccated

溶解性

water: soluble

輸送温度

ambient

保管温度

2-8°C

SMILES記法

O=C(C=CC1=O)N1CCOCCOCCOCCN2C(C=CC2=O)=O

InChI

1S/C16H20N2O7/c19-13-1-2-14(20)17(13)5-7-23-9-11-25-12-10-24-8-6-18-15(21)3-4-16(18)22/h1-4H,5-12H2

InChI Key

OYRSKXCXEFLTEY-UHFFFAOYSA-N

詳細

BM(PEG)2 and BM(PEG)3 are homobifunctional, maleimide crosslinkers for conjugation between sulfhydryl groups (-SH). Such bismaleimide crosslinkers are commonly used to explore and characterize protein structure (i.e. oligomerization) or protein interactions. Because BM(PEG)2 and BM(PEG)3 have the same reactivity but differ in length, the relative success of these and similar reagents in forming crosslinks between sites in a protein oligomer or interaction can assist in determining intra- and intermolecular distances.

特徴および利点

  • Reactive groups: maleimide (both ends)
  • Reactive towards: sulfhydryl groups
  • Long, pegylated, sulfhydryl-to-sulfhydryl crosslinkers, composed of maleimide groups and 3-unit polyethylene glycol spacer arm
  • PEG spacers provide unique advantages, including enhanced solubility, increased stability, reduced tendency toward aggregation and reduced immunogenicity
  • Pure compounds with defined structure and molecular weight, ensuring reproducible protein-modification effects
  • Ideal for small molecule or peptide conjugations

注意

This product is sensitive to moisture. The vial is packaged in a resealable bag with a desiccant to reduce exposure to moisture. After cold storage, equilibrate the vial to room temperature before opening to reduce condensation inside the vial. Make fresh solutions. Storage of stock solutions is not recommended. After use, return the vial to the resealable bag. Close the bag and store the product at the recommended temperature.

ピクトグラム

Exclamation mark

シグナルワード

Warning

危険有害性情報

危険有害性の分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

ターゲットの組織

Respiratory system

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

803596-50MG:


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ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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