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Merck

54965

Sigma-Aldrich

(±)-3-ヒドロキシ酪酸ナトリウム

≥99.0% (NT)

別名:

(±)-3-ヒドロキシ酪酸 ナトリウム塩

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10 G
¥11,300
50 G
¥44,400

¥11,300


出荷可能日2025年4月14日詳細


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10 G
¥11,300
50 G
¥44,400

About This Item

化学式:
CH3CH(OH)CH2COONa
CAS番号:
分子量:
126.09
Beilstein:
4824866
EC Number:
MDL番号:
UNSPSCコード:
12352100
PubChem Substance ID:
NACRES:
NA.22

¥11,300


出荷可能日2025年4月14日詳細


バルクの問い合わせ

品質水準

アッセイ

≥99.0% (NT)

mp

167-170 °C

官能基

hydroxyl

SMILES記法

[Na+].CC(O)CC([O-])=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

InChI Key

NBPUSGBJDWCHKC-UHFFFAOYSA-M

関連するカテゴリー

アプリケーション

(±)-3-ヒドロキシ酪酸ナトリウムは、肝臓の脂肪酸β酸化に関与している線維芽細胞成長因子 21(FGF21)に及ぼす酪酸の効果を把握する研究に使用されています。[1]これは、ポリ(3-ヒドロキシ酪酸塩)の調製に使用する場合があります。[2]

保管分類コード

11 - Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

54965-INTR-F:
54965-50G-F:
54965-BULK-F:
54965-VAR-F:
54965-10G-F:


最新バージョンのいずれかを選択してください:

試験成績書(COA)

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Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3.
Li H, et al.
Diabetes, 61(4), 797-806 (2012)
Novel synthesis of poly (3-hydroxybutyrate).
Juzwa M and Jedli?ski Z.
Macromolecules, 39(13), 4627-4630 (2006)
Shengying Pan et al.
Behavioural pharmacology, 31(4), 322-332 (2020-01-03)
β-hydroxybutyrate, a ketone body metabolite, has been shown to suppress depression-like behavior in rodents. In this study, we examined its antidepressive property in acute and chronic administration modes in mice by using forced swim test and tail suspension test. Results
Roman Tyzio et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(1), 34-45 (2011-01-07)
GABA depolarizes immature neurons because of a high [Cl(-)](i) and orchestrates giant depolarizing potential (GDP) generation. Zilberter and coworkers (Rheims et al., 2009; Holmgren et al., 2010) showed recently that the ketone body metabolite DL-3-hydroxybutyrate (DL-BHB) (4 mM), lactate (4
Brian A Parker et al.
International journal of molecular sciences, 19(8) (2018-08-04)
The clinical benefit of ketosis has historically and almost exclusively centered on neurological conditions, lending insight into how ketones alter mitochondrial function in neurons. However, there is a gap in our understanding of how ketones influence mitochondria within skeletal muscle

質問

1–4/4 質問  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 回答
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 回答
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      役に立ちましたか?

  3. Is your hydroxybutyrate chemically synthesized or produced from fermentation?

    1 回答
    1. This product is produced from chemical synthesis and fermentation from cell culture. This information is presented on the lot specific Certificate of Origin. Please navigate to the ‘DOCUMENTATION’ section of the Product Detail Page to access a Certificate under the ‘Certificate of Origin’ tab:
      https://www.sigmaaldrich.com/product/aldrich/54965#product-documentation

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  4. What is the ratio of the two isomers in product 54965?

    1 回答
    1. Product 54965 is considered a racemic material, which means that there is approximately a 50/50 ratio of the two isomers. However, it is not tested or characterized, so it cannot be guaranteed to be exactly 50/50, but it should be close.

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