43798

Ethyl 1,3-dithiolane-2-carboxylate

≥98.0%

• 別名: Glyoxylic acid ethyl ester ethylene mercaptal
• 実験式（ヒル表記法）: C₆H₁₀O₂S₂
• CAS番号: 20461-99-8
• 分子量: 178.27
• Beilstein: 118157
• EC Number: 243-837-9
• MDL番号: MFCD00005411
• UNSPSCコード: 12352100
• PubChem Substance ID: 24867412

特性

• アッセイ: ≥98.0%
• 屈折率: n20/D 1.539 (lit.); n20/D 1.540
• bp: 85 °C/0.1 mmHg (lit.)
• 密度: 1.249 g/mL at 25 °C (lit.)
• SMILES記法: CCOC(=O)C1SCCS1
• InChI: 1S/C6H10O2S2/c1-2-8-5(7)6-9-3-4-10-6/h6H,2-4H2,1H3
• InChI Key: OMCSHTHLIQOHDD-UHFFFAOYSA-N

詳細

詳細

Ethyl 1,3-dithiolane-2-carboxylate is an α-keto acid equivalent. It participates in the conjugate additions to enones. It is a bulky equivalent of acetate undergoing syn-selective aldol reactions. Anion derived from ethyl 1,3-dithiolane-2-carboxylate participates as nucleophile during the total synthesis of the corynanthe alkaloid dihydrocorynantheol and the formal syntheses of the indole alkaloids tacamonine, rhynchophylline and hirsutine. It also participates in the conjugate addition of enolates to phenylglycinol-derived α,β-unsaturated δ-lactams.

その他情報

α-Keto acid equivalent; conjugate additions to enones ; bulky equivalent of acetate undergoing syn-selective aldol reactions

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): 235.4 °F - closed cup
• 引火点(℃): 113 °C - closed cup
• 個人用保護具 (PPE): Eyeshields, Gloves