コンテンツへスキップ
Merck

WT1

Wilms tumor 1

別名:
AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33
Species:
Human WT1 (7490), Mouse Wt1 (22431), Rat Wt1 (24883), domestic guinea pig Wt1 (100716139), dog WT1 (609253), sheep WT1 (100101227), naked mole-rat Wt1 (101714640), cow WT1 (280959), chicken WT1 (396139), cow WT1 (782183) ...詳細
UniProtKB ID:
P19544, A8K6S1, B3KSA5, Q15881, Q16256, Q16575, Q4VXV4, Q4VXV5
遺伝子ID:
  • Human(7490) Summary: This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation site upstream of and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Oct 2010]
  • Mouse(22431) Wilms tumor 1 homolog
  • Rat(24883) Wilms tumor 1
  • domestic guinea pig(100716139) Wilms tumor 1
  • dog(609253) Wilms tumor 1
  • sheep(100101227) Wilms tumor 1
  • naked mole-rat(101714640) Wilms tumor 1
  • cow(280959) Wilms tumor 1
  • chicken(396139) Wilms tumor 1
  • cow(782183) Wilms tumor 1
  • cow(614584) Wilms tumor 1
  • domestic cat(101088518) Wilms tumor 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
MAB4234
抗ウィルムス腫瘍抗体、NT、クローン6F-H2, clone 6F-H2, Chemicon®, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
05-753
抗WT1抗体、クローン6F-H2, clone 6F-H2, Upstate®, from mouse,
交差性
human
アプリケーション
immunocytochemistry
immunohistochemistry
western blot
MAB4234-C
抗ウィルムス腫瘍抗体、NT、クローン6F-H2、腹水フリー, clone 6F-H2, from mouse,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB2108752
抗WT1抗体, affinity isolated antibody,
交差性
dog, human, mouse, rabbit, rat
アプリケーション
immunohistochemistry
western blot
HPA053848
Anti-WT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence

Proteins

製品番号
詳細
Species
SRP2082
WT-1 (+KTS) ヒト, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Species
human
SRP2083
WT-1 (-KTS) ヒト, recombinant, expressed in insect cells, ≥60% (SDS-PAGE),
Species
human

esiRNA

製品番号
詳細
Species
EHU083661
MISSION® esiRNA, targeting human WT1,
Species
human