TXNRD1
thioredoxin reductase 1
別名:
GRIM-12, TR, TR1, TRXR1, TXNR
Species:
Human TXNRD1 (7296), Mouse Txnrd1 (50493), Rat Txnrd1 (58819), Horse TXNRD1 (100067923), domestic cat TXNRD1 (101085222), domestic guinea pig Txnrd1 (100718723), Domestic Rabbit TXNRD1 (100356179), naked mole-rat Txnrd1 (101700382), dog TXNRD1 (474536), sheep TXNRD1 (101112970) ...詳細
UniProtKB ID:
遺伝子ID:
- Human(7296) Summary: This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(50493) thioredoxin reductase 1
- Rat(58819) thioredoxin reductase 1
- Horse(100067923) thioredoxin reductase 1
- domestic cat(101085222) thioredoxin reductase 1
- domestic guinea pig(100718723) thioredoxin reductase 1
- Domestic Rabbit(100356179) thioredoxin reductase 1
- naked mole-rat(101700382) thioredoxin reductase 1
- dog(474536) thioredoxin reductase 1
- sheep(101112970) thioredoxin reductase 1
- cow(282388) thioredoxin reductase 1
- chicken(418082) thioredoxin reductase 1
- Zebrafish(352924) thioredoxin reductase 1
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Activity Assay
製品番号
詳細
Species
Antibodies
製品番号
詳細
交差性
アプリケーション
抗TXNRD1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
western blot
western blot
抗TXNRD1抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot
抗TXNRD1抗体 マウス宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
western blot
Anti-Thioredoxin reductase 1 (TXNRD1 ) Antibody, clone 7P1J4, Rabbit Monoclonal, ,
交差性
human, rat
アプリケーション
western blot
Proteins
製品番号
詳細
Species
チオレドキシンレダクターゼ ラット肝臓由来, buffered aqueous glycerol solution, ≥100 units/mg protein (Bradford),
Species
rat