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Merck

TNF

tumor necrosis factor

別名:
DIF, TNF-alpha, TNFA, TNFSF2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7124) Summary: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
  • Mouse(21926) tumor necrosis factor
  • Rat(24835) tumor necrosis factor
  • dog(403922) tumor necrosis factor
  • domestic cat(493755) tumor necrosis factor
  • Horse(100033834) tumor necrosis factor
  • Goat(100861232) tumor necrosis factor alpha
  • cow(280943) tumor necrosis factor
  • sheep(443540) tumor necrosis factor
  • Domestic Rabbit(100009088) tumor necrosis factor
  • domestic guinea pig(100135630) tumor necrosis factor
  • naked mole-rat(101718432) tumor necrosis factor

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ELISA

製品番号
詳細
Species
マウス腫瘍壊死因子αELISAキット, for serum, plasma and cell culture supernatant,
Species
mouse
Rat Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Species
rat
Rat Tumor Necrosis Factor α ELISA Kit, for cell and tissue lysates,
Species
rat
Canine TNF / Tumor Necrosis Factor ELISA Kit, for serum, plasma and cell culture supernatants,
Species
dog
Porcine Tumor Necrosis Factor α ELISA Kit, for serum, plasma and cell culture supernatant,
Species

Small Molecule - Antagonist

製品番号
詳細
Species
Podocarpic acid, 98%,
Species
human
アビエチン酸, technical, ~75% (GC),
Species
human
フォルスコリン, from Coleus forskohlii, ≥98% (HPLC), powder,
Species
human
SKF-86002, ≥98% (HPLC), solid,
Species
human, rat
ミリセチン, ≥96.0%, crystalline,
Species
rat, mouse, human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Tumor Necrosis Factor-α Antibody, Chemicon®, from rabbit,
交差性
rat
アプリケーション
ELISA
western blot
Anti-TNF-α antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-Tumor Necrosis Factor-α Antibody, Chemicon®, from rabbit,
交差性
mouse
アプリケーション
ELISA
neutralization

western blot
抗腫瘍壊死因子-α ウサギ宿主抗体, IgG fraction of antiserum, buffered aqueous solution,
交差性
human
アプリケーション
dot blot
microarray

neutralization
Anti-TNFA antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunofluorescence

immunohistochemistry

Small Molecule - Inhibitor

製品番号
詳細
Species
SPD304, ≥98% (HPLC), solid,
Species
mouse, rat, human
SKF-86002, ≥98% (HPLC), solid,
Species
human, rat
ミリセチン, ≥96.0%, crystalline,
Species
rat, mouse, human
ミリセチン, ≥96.0% (HPLC),
Species
rat, mouse, human
(−)-サリドマイド, >98%, solid,
Species
human, mouse, rat

Proteins

製品番号
詳細
Species
腫瘍壊死因子-α ヒト, Xeno-free, recombinant, expressed in HEK 293 cells, suitable for cell culture,
Species
human
TNF-α ヒト, Animal-component free, recombinant, expressed in E. coli, suitable for cell culture,
Species
human
腫瘍壊死因子-α ヒト, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
Species
human
腫瘍壊死因子-α マウス由来, TNF-α, recombinant, expressed in E. coli, powder, suitable for cell culture,
Species
mouse
腫瘍壊死因子-α、ヒト(hTNF-α), recombinant (yeast),
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TNF,
Species
human
MISSION® esiRNA, targeting mouse Tnf,
Species
mouse