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Merck

THRB

thyroid hormone receptor, beta

別名:
C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7068) Summary: The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21834) thyroid hormone receptor beta
  • Rat(24831) thyroid hormone receptor beta
  • Domestic Rabbit(100303763) thyroid hormone receptor, beta
  • chicken(396431) thyroid hormone receptor, beta
  • cow(788329) thyroid hormone receptor, beta
  • domestic cat(101084821) thyroid hormone receptor, beta
  • Horse(100051615) thyroid hormone receptor, beta
  • dog(403599) thyroid hormone receptor, beta
  • naked mole-rat(101719651) thyroid hormone receptor, beta
  • domestic guinea pig(100721125) thyroid hormone receptor, beta
  • Zebrafish(30607) thyroid hormone receptor beta

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Small Molecule - Agonist

製品番号
詳細
Species
レボチロキシン, United States Pharmacopeia (USP) Reference Standard,
Species
human
3,3',5-トリヨード-L-チロニン(T3) 溶液, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
L-チロキシン, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
リオチロニン, United States Pharmacopeia (USP) Reference Standard,
Species
human
レボチロキシンナトリウム, United States Pharmacopeia (USP) Reference Standard,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
3,3′,5-トリヨード-L-チロニン ナトリウム塩, powder, BioReagent, suitable for cell culture,
Species
rat, human
3,3′,5-トリヨード-L-チロニン, ≥95% (HPLC), powder,
Species
rat, human
3,3′,5-トリヨード-L-チロニン ナトリウム塩, γ-irradiated, powder, suitable for, suitable for cell culture,
Species
rat, human
3,3',5-トリヨードチロ酢酸, ≥90%,
Species
rat, human
L-チロキシン, ≥98% (HPLC),
Species
human, mouse, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Thyroid Hormone Receptor β-1 Antibody, from rabbit, purified by affinity chromatography,
交差性
human, mouse, rat
アプリケーション
western blot
Anti-Thyroid Hormone Receptor β, N-Terminal antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

western blot
抗THRB抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
交差性
human
アプリケーション
immunofluorescence
Anti-phospho-TR-β1 (pSer142) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
ELISA
western blot
抗THRB抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
canine, human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Blocker

製品番号
詳細
Species
3,3′,5-トリヨード-L-チロニン ナトリウム塩, powder, BioReagent, suitable for cell culture,
Species
rat, human
3,3′,5-トリヨード-L-チロニン, ≥95% (HPLC), powder,
Species
rat, human
3,3′,5-トリヨード-L-チロニン ナトリウム塩, γ-irradiated, powder, suitable for, suitable for cell culture,
Species
rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human THRB,
Species
human