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Merck

PDE3A

phosphodiesterase 3A, cGMP-inhibited

別名:
CGI-PDE, CGI-PDE A, CGI-PDE-A
Species:
UniProtKB ID:
遺伝子ID:
  • Human(5139) Summary: This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(54611) phosphodiesterase 3A, cGMP inhibited
  • Rat(50678) phosphodiesterase 3A, cGMP inhibited
  • domestic cat(101088586) phosphodiesterase 3A, cGMP-inhibited
  • naked mole-rat(101704787) phosphodiesterase 3A, cGMP-inhibited
  • Domestic Rabbit(100009330) phosphodiesterase 3A, cGMP-inhibited
  • Horse(100034086) phosphodiesterase 3A, cGMP-inhibited
  • sheep(101115870) phosphodiesterase 3A, cGMP-inhibited
  • Zebrafish(567051) phosphodiesterase 3A, cGMP-inhibited
  • cow(536636) phosphodiesterase 3A, cGMP-inhibited
  • chicken(418185) phosphodiesterase 3A, cGMP-inhibited
  • domestic guinea pig(100302667) phosphodiesterase 3A, cGMP inhibited

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗PDE3A抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Anti-PDE3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry
Monoclonal Anti-PDE3A antibody produced in mouse, clone 5C12, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
シロスタゾール, United States Pharmacopeia (USP) Reference Standard,
Species
human
ミルリノン, United States Pharmacopeia (USP) Reference Standard,
Species
human
シロスタゾール, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
アムリノン, United States Pharmacopeia (USP) Reference Standard,
Species
human
シロスタゾール, ≥98% (HPLC), powder,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PDE3A,
Species
human
MISSION® esiRNA, targeting mouse Pde3a,
Species
mouse