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Merck

PARP1

poly (ADP-ribose) polymerase 1

別名:
ADPRT, ADPRT 1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(142) Summary: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11545) poly (ADP-ribose) polymerase family, member 1
  • Rat(25591) poly (ADP-ribose) polymerase 1
  • Thale Cress(817690) poly [ADP-ribose] polymerase 2
  • chicken(396199) poly (ADP-ribose) polymerase 1
  • Zebrafish(560788) poly (ADP-ribose) polymerase family, member 1
  • sheep(100135697) poly (ADP-ribose) polymerase 1
  • domestic cat(101081434) poly (ADP-ribose) polymerase 1
  • Horse(100058523) poly (ADP-ribose) polymerase 1
  • dog(490385) poly (ADP-ribose) polymerase 1
  • domestic guinea pig(100733925) poly (ADP-ribose) polymerase 1
  • naked mole-rat(101703207) poly (ADP-ribose) polymerase 1
  • cow(286764) poly (ADP-ribose) polymerase 1

Custom & Knockdown Gene Products

Antibodies

製品番号
詳細
交差性
アプリケーション
抗ポリADPリボース抗体、クローン10H, clone 10H, from mouse,
交差性
human
アプリケーション
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-PARP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-PARP1 antibody produced in mouse, clone 3G4, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
immunofluorescence

western blot
抗cleaved PARP1抗体 クローン2G13 ZooMAb®ウサギモノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
flow cytometry
immunocytochemistry

immunohistochemistry

western blot
Anti-PARP (Cleaved-Asp214) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse
アプリケーション
ELISA
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
ベンズアミド, 99%,
Species
human
3-アミノベンズアミド, ≥99% (TLC),
Species
mouse
ベンズアミド, purified by sublimation, ≥99.5%,
Species
human
6-(5H)-フェナントリジノン, technical grade,
Species
human
ニコチンアミド, BioReagent, suitable for cell culture, suitable for insect cell culture,
Species
human

Proteins

製品番号
詳細
Species
PARP1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Species
human
PARP-1 ヒト, recombinant, expressed in E. coli,
Species
human
Monoclonal Anti-PARP1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2220, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human
Monoclonal Anti-PARP1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2209, purified immunoglobulin, buffered aqueous glycerol solution,
Species
human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human PARP1,
Species
human
MISSION® esiRNA, targeting mouse Parp1,
Species
mouse