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Merck

OPTN

optineurin

別名:
ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
Species:
UniProtKB ID:
遺伝子ID:
  • Human(10133) Summary: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
  • Mouse(71648) optineurin
  • Rat(246294) optineurin
  • domestic guinea pig(100722896) optineurin
  • naked mole-rat(101725616) optineurin
  • domestic cat(101087414) optineurin
  • cow(534150) optineurin
  • sheep(101106703) optineurin
  • chicken(374079) optineurin
  • dog(478003) optineurin
  • Zebrafish(336159) optineurin

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗OPTN ウサギ宿主抗体, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗OPTN ウサギ宿主抗体, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunofluorescence
immunohistochemistry

western blot
抗OPTN抗体 マウス宿主抗体, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
immunofluorescence
western blot
抗OPTN抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
dog, guinea pig, horse, human, mouse, rabbit, rat
アプリケーション
western blot
抗OPTN抗体(ab2) ウサギ宿主抗体, affinity isolated antibody,
交差性
guinea pig, human
アプリケーション
western blot

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human OPTN,
Species
human