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Merck

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

別名:
CLMF, IL-12A, NFSK, NKSF1, P35
Species:
UniProtKB ID:
遺伝子ID:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • domestic guinea pig(100379543) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Zebrafish(445410) interleukin 12a
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Custom & Knockdown Gene Products

ELISA

製品番号
詳細
Species
Human IL-12 p70 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Mouse IL-12 P40/70 ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
Rhesus Macaque IL12A / IL12B ELISA Kit, ,
Species
Porcine IL12A / IL12B ELISA Kit, ,
Species

Antibodies

製品番号
詳細
交差性
アプリケーション
抗インターロイキン-12抗体 ヤギ宿主抗体, IgG fraction of antiserum,
交差性
mouse
アプリケーション
neutralization
western blot
Anti-IL-12A Antibody, clone 1G10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
baboon, bovine, canine, feline, goat, human, monkey, mouse, porcine, sheep
アプリケーション
affinity binding assay
flow cytometry

western blot
抗インターロイキン-12抗体 ヤギ宿主抗体, IgG fraction of antiserum, lyophilized powder,
交差性
human
アプリケーション
neutralization
Anti-IL-12 alpha Antibody, from rabbit, purified by affinity chromatography,
交差性
human
アプリケーション
immunohistochemistry
western blot

Proteins

製品番号
詳細
Species
IL-12 ヒト, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
IL-35(マウス):FC(ヒト), recombinant, expressed in CHO cells,
Species
mouse
インターロイキン-12 ヒト, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
human
インターロイキン-12 マウス由来, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human IL12A,
Species
human
MISSION® esiRNA, targeting mouse Il12a,
Species
mouse