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Merck

IGF1R

insulin-like growth factor 1 receptor

別名:
CD221, IGFIR, IGFR, JTK13
Species:
Human IGF1R (3480), Mouse Igf1r (16001), Rat Igf1r (25718), domestic guinea pig Igf1r (100734840), chicken IGF1R (395889), naked mole-rat Igf1r (101710224), Horse IGF1R (100055698), domestic cat IGF1R (100500937), cow IGF1R (281848), dog IGF1R (442951)
UniProtKB ID:
P08069, B1B5Y2, Q14CV2, Q9UCC0
遺伝子ID:
  • Human(3480) Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]
  • Mouse(16001) insulin-like growth factor I receptor
  • Rat(25718) insulin-like growth factor 1 receptor
  • domestic guinea pig(100734840) insulin-like growth factor 1 receptor
  • chicken(395889) insulin-like growth factor 1 receptor
  • naked mole-rat(101710224) insulin-like growth factor 1 receptor
  • Horse(100055698) insulin-like growth factor 1 receptor
  • domestic cat(100500937) insulin-like growth factor 1 receptor
  • cow(281848) insulin-like growth factor 1 receptor
  • dog(442951) insulin-like growth factor 1 receptor
  • sheep(443002) insulin-like growth factor 1 receptor

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ELISA

製品番号
詳細
Species
RAB0230
Human IGF-I R ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
ABE332
Anti-phospho-IGF-1R (Tyr1161/Tyr1165/Tyr1166) Antibody, from rabbit, purified by affinity chromatography,
交差性
xenopus, chicken, human, mouse, pig, porcine, rat, zebrafish
アプリケーション
cell based assay
western blot
SAB2101136
抗IGF1R抗体 ウサギ宿主抗体, affinity isolated antibody,
交差性
bovine, dog, horse, human, pig, sheep
アプリケーション
immunofluorescence
immunohistochemistry
western blot
ZRB1482
Anti-IGF-1R β Antibody, clone 1D18 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, mouse, rat
アプリケーション
affinity binding assay
flow cytometry
immunohistochemistry
western blot
SAB4300359
Anti-IGF1R (Ab-1161) antibody produced in rabbit, affinity isolated antibody,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
immunohistochemistry
western blot
MAB1120
Anti-Insulin-like Growth Factor-1 Receptor Antibody, α-subunit, clone 24-31, clone 24-31, Chemicon®, from mouse,
交差性
human
アプリケーション
immunohistochemistry
immunoprecipitation (IP)

Small Molecule - Inhibitor

製品番号
詳細
Species
T9576
Picropodophyllotoxin, ≥96% (HPLC), powder,
Species
human
T7697
I-OMe-チロホスチンAG 538, solid,
Species
human

Proteins

製品番号
詳細
Species
S1820
Ser-Phe-Leu-Leu-Arg-Asn-アミド トリフルオロアセタート塩, ≥98% (HPLC), lyophilized powder,
Species
human
I4657
インスリン様成長因子-I レセプター ヒト, ≥95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Species
human
14-465-M
IGF-IR (δ1-958) Protein, active, 20 µg, Active, N-terminal His6-tagged, recombinant human IGF-IR residues 959-end, for use in Kinase Assays.,
Species
human

esiRNA

製品番号
詳細
Species
EHU028861
MISSION® esiRNA, targeting human IGF1R,
Species
human
EMU017201
MISSION® esiRNA, targeting mouse Igf1r,
Species
mouse

Small Molecule - Substrate

製品番号
詳細
Species
12-527
IGF-IRtide, Substrate for in vitro IGF-1R kinase assays.,
Species
human