HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
別名:
HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
Species:
Human HIF1A (3091), Mouse Hif1a (15251), Rat Hif1a (29560), dog HIF1A (480348), domestic guinea pig Hif1a (100713113), naked mole-rat Hif1a (101715845), Domestic Rabbit HIF1A (100009579), sheep HIF1A (443519), cow HIF1A (281814), domestic cat HIF1A (101083686)
UniProtKB ID:
遺伝子ID:
- Human(3091) Summary: This gene encodes the alpha subunit of transcription factor hypoxia-inducible factor-1 (HIF-1), which is a heterodimer composed of an alpha and a beta subunit. HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes, including those involved in energy metabolism, angiogenesis, apoptosis, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. HIF-1 thus plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2011]
- Mouse(15251) hypoxia inducible factor 1, alpha subunit
- Rat(29560) hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- dog(480348) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic guinea pig(100713113) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- naked mole-rat(101715845) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- Domestic Rabbit(100009579) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- sheep(443519) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- cow(281814) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- domestic cat(101083686) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
- chicken(374177) hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
製品番号
詳細
Species
Human HIF-1 alpha ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human
Antibodies
製品番号
詳細
交差性
アプリケーション
Anti-HIF-1α Antibody, clone 2B14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
交差性
human, monkey
アプリケーション
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
抗HIF1A ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗低酸素誘導因子1α抗体、クローン H1α67, clone H1alpha67, Chemicon®, from mouse,
交差性
ferret, human, mouse, rat
アプリケーション
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
抗HIF1A ウサギ宿主抗体, ,
交差性
bovine, human, mouse, rat
アプリケーション
ChIP
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-HIF-1 alpha antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM242, purified immunoglobulin,
交差性
human
アプリケーション
immunohistochemistry
western blot
western blot