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Merck

GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

別名:
CAE2, ECA2, GEFSP3
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2566) Summary: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(14406) gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
  • Rat(29709) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Horse(100059571) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • sheep(101118526) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • Zebrafish(553402) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • chicken(396289) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • dog(489141) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic cat(100286791) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • cow(282240) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • domestic guinea pig(100723005) gamma-aminobutyric acid (GABA) A receptor, gamma 2
  • naked mole-rat(101718598) gamma-aminobutyric acid (GABA) A receptor, gamma 2

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Small Molecule - Agonist

製品番号
詳細
Species
メプロバマート 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
オキサゼパム, ,
Species
human
メプロバマート, United States Pharmacopeia (USP) Reference Standard,
Species
human
メプロバマート, analytical standard,
Species
human
γ-アミノ酪酸, ≥99%,
Species
human, rat

Small Molecule - Allosteric Modulator

製品番号
詳細
Species
ゾルピデム 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
ザレプロン 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Zaleplon, United States Pharmacopeia (USP) Reference Standard,
Species
human
システム適合性用ゾルピデム, CRS, European Pharmacopoeia (EP) Reference Standard,
Species
human
5α-Pregnan-3α-ol-11,20-dione, powder, ≥98% (TLC),
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
エチオコラン-3α-オール-17-オン, ,
Species
human, rat
ゾルピデム, ≥98% (HPLC), solid,
Species
human, rat
フルマゼニル, United States Pharmacopeia (USP) Reference Standard,
Species
human
フルニトラゼパム, ,
Species
human
クロナゼパム, powder,
Species
human, rat

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-GABA A Receptor γ2 Antibody, cytoplasmic loop, Chemicon®, from rabbit,
交差性
rat
アプリケーション
immunoprecipitation (IP)
western blot
Anti-GABA(A) receptor subunit gamma-2 Antibody, clone 10F10-C1-B8, clone 10F10-C1-B8, from mouse,
交差性
rat
アプリケーション
immunocytochemistry
western blot
Anti-GABA(A) receptor subunit gamma-2 Antibody, serum, from rabbit,
交差性
human, rat
アプリケーション
western blot
Anti- GABAA Antibody γ2 Subunit, clone KC4-8A7, clone KC4-8A7, from mouse,
交差性
bovine, human, mouse, rat
アプリケーション
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
抗GABRG2抗体 ヤギ宿主抗体, affinity isolated antibody, buffered aqueous solution,
交差性
bovine, human, mouse, rat
アプリケーション
ELISA
western blot

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
エチオコラン-3α-オール-17-オン, ,
Species
human, rat
Ganaxolone, ≥98% (HPLC), solid,
Species
human, mouse
5α-プレグナン-3α-オール-20-オン, solid,
Species
human, mouse, rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human GABRG2,
Species
human