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Merck

G6PC

glucose-6-phosphatase, catalytic subunit

別名:
G6PC1, G6PT, GSD1, GSD1a
Species:
UniProtKB ID:
遺伝子ID:
  • Human(2538) Summary: Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P, inorganic phosphate, and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC, G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease, also known as von Gierke disease, is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq, Feb 2011]
  • Mouse(14377) glucose-6-phosphatase, catalytic
  • Rat(25634) glucose-6-phosphatase, catalytic subunit
  • naked mole-rat(101708598) glucose-6-phosphatase, catalytic subunit
  • cow(538710) glucose-6-phosphatase, catalytic subunit
  • domestic guinea pig(100720420) glucose-6-phosphatase, catalytic subunit
  • dog(403492) glucose-6-phosphatase, catalytic subunit
  • domestic cat(723970) glucose-6-phosphatase, catalytic subunit

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Antibodies

製品番号
詳細
交差性
アプリケーション
抗G6PC抗体 ウサギ宿主抗体, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti--G6PC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5817, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
Monoclonal Anti--G6PC antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL5818, purified immunoglobulin, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
抗G6PC抗体, affinity isolated antibody,
交差性
dog, human, pig, sheep
アプリケーション
immunohistochemistry
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
クロロゲン酸, ≥95% (titration),
Species
rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting mouse G6pc,
Species
mouse
MISSION® esiRNA, targeting human G6PC,
Species
human