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Merck

CYP2C8

cytochrome P450, family 2, subfamily C, polypeptide 8

別名:
CPC8, CYPIIC8, MP-12/MP-20
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1558) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
交差性
human
アプリケーション
immunohistochemistry
western blot
Anti-Cytochrome P450 2C8 antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
western blot
Anti-CYP2C8 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-CYP450 Pan 2C Antibody, serum, Chemicon®,
交差性
human
アプリケーション
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
テルフェナジン, ,
Species
mouse, rat, human

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human CYP2C8,
Species
human