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Merck

CHRNG

cholinergic receptor, nicotinic, gamma (muscle)

別名:
ACHRG
Species:
UniProtKB ID:
遺伝子ID:
  • Human(1146) Summary: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.[provided by RefSeq, Sep 2009]
  • Mouse(11449) cholinergic receptor, nicotinic, gamma polypeptide
  • Rat(25753) cholinergic receptor, nicotinic, gamma (muscle)
  • cow(281689) cholinergic receptor, nicotinic, gamma (muscle)
  • Zebrafish(325080) cholinergic receptor, nicotinic, gamma
  • dog(486163) cholinergic receptor, nicotinic, gamma (muscle)
  • domestic cat(101098733) cholinergic receptor, nicotinic, gamma (muscle)
  • chicken(429151) cholinergic receptor, nicotinic, gamma
  • naked mole-rat(101706620) cholinergic receptor, nicotinic, gamma (muscle)
  • sheep(101102965) cholinergic receptor, nicotinic, gamma (muscle)
  • domestic guinea pig(100733530) cholinergic receptor, nicotinic, gamma (muscle)

Custom & Knockdown Gene Products

Small Molecule - Agonist

製品番号
詳細
Species
デカメトニウムブロミド, crystalline,
Species
human

Small Molecule - Antagonist

製品番号
詳細
Species
Cisatracurium besylate, United States Pharmacopeia (USP) Reference Standard,
Species
human
ツボクラリン 塩酸塩 五水和物, ≥97%,
Species
human
ベクロニウムブロミド, ,
Species
human
ロクロニウム 臭化物, United States Pharmacopeia (USP) Reference Standard,
Species
human
(+)-Tubocurarine chloride pentahydrate, ≥97.0% (TLC),
Species
human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-CHRNG, N-terminal region antibody produced in rabbit, IgG fraction of antiserum,
交差性
dog, human, rabbit
アプリケーション
western blot