コンテンツへスキップ
Merck

ABCG2

ATP-binding cassette, sub-family G (WHITE), member 2

別名:
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1
Species:
Human ABCG2 (9429), Mouse Abcg2 (26357), Rat Abcg2 (312382), domestic guinea pig Abcg2 (100723442), domestic cat ABCG2 (101094017), chicken ABCG2 (423767), dog ABCG2 (478472), Horse ABCG2 (100034164), cow ABCG2 (536203), sheep ABCG2 (780508) ...詳細
UniProtKB ID:
Q9UNQ0, A0A1W3, A8K1T5, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64
遺伝子ID:
  • Human(9429) Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(26357) ATP-binding cassette, sub-family G (WHITE), member 2
  • Rat(312382) ATP-binding cassette, subfamily G (WHITE), member 2
  • domestic guinea pig(100723442) ATP-binding cassette, sub-family G (WHITE), member 2
  • domestic cat(101094017) ATP-binding cassette, sub-family G (WHITE), member 2
  • chicken(423767) ATP-binding cassette, sub-family G (WHITE), member 2
  • dog(478472) ATP-binding cassette, sub-family G (WHITE), member 2
  • Horse(100034164) ATP-binding cassette, sub-family G (WHITE), member 2
  • cow(536203) ATP-binding cassette, sub-family G (WHITE), member 2
  • sheep(780508) ATP-binding cassette, sub-family G (WHITE), member 2
  • Domestic Rabbit(100008640) ATP-binding cassette, sub-family G (WHITE), member 2
  • Goat(100860857) ATP-binding cassette, sub-family G (WHITE), member 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

製品番号
詳細
交差性
アプリケーション
ZRB1217
抗BCRP(ABCG2)抗体 クローン10K5 ZooMAb® ウサギ・モノクローナル, recombinant, expressed in HEK 293 cells,
交差性
human, mouse
アプリケーション
immunocytochemistry
immunohistochemistry
western blot
MAB4145
Anti-BCRP Antibody, clone BXP-34, culture supernatant, clone BXP-34, Chemicon®,
交差性
human
アプリケーション
immunocytochemistry
immunohistochemistry
SAB1403023
Monoclonal Anti-ABCG2 antibody produced in mouse, clone 1G1, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
SAB5701106
Anti-ABCG2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
western blot
SAB5700094
Anti-ABCG2 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
western blot

Cell Lines

製品番号
詳細
Species
SBVT17
SB-BCRP-HEK293, ,
Species
human
MTOX1304
イヌMDR1ノックアウト、ヒトBCRPノックインMDCKII細胞, ,
Species
human
MTOX1002
BCRP Knockout Caco-2 Cells, one vial,
Species
human
MTOX1021
HepaRG™ Cells BCRP (-/-), one vial,
Species
human
SBVT30
SB-cyBcrp-HEK293, ,
Species

Proteins

製品番号
詳細
Species
SBPE05
SB-BCRP-M-PREDEASY-ATPase kit, membrane based kit for Human BCRP ATPase Transport Assays,
Species
human

esiRNA

製品番号
詳細
Species
EHU012921
MISSION® esiRNA, targeting human ABCG2,
Species
human
EMU090051
MISSION® esiRNA, targeting mouse Abcg2,
Species
mouse