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Merck

Antibacterial alkoxybenzamide inhibitors of the essential bacterial cell division protein FtsZ.

Bioorganic & medicinal chemistry letters (2008-12-10)
Lloyd G Czaplewski, Ian Collins, E Andrew Boyd, David Brown, Stephen P East, Mihaly Gardiner, Rowena Fletcher, David J Haydon, Vincent Henstock, Peter Ingram, Clare Jones, Caterina Noula, Leanne Kennison, Chris Rockley, Valerie Rose, Helena B Thomaides-Brears, Rebecca Ure, Mark Whittaker, Neil R Stokes
ABSTRACT

3-Methoxybenzamide is a weak inhibitor of the essential bacterial cell division protein FtsZ. Exploration of the structure-activity relationships of 3-methoxybenzamide analogues led to the identification of potent anti-staphylococcal compounds.

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Sigma-Aldrich
Ciprofloxacin, ≥98% (HPLC)
Sigma-Aldrich
Mupirocin, ≥92% (HPLC), powder
Sigma-Aldrich
3-Methoxybenzoic acid, ReagentPlus®, 99%
Supelco
Ciprofloxacin, VETRANAL®, analytical standard
Sigma-Aldrich
3-Methoxybenzamide, 97%