PHR9070

Favipiravir

certified reference material, TraceCERT^®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

• Sinonimo/i: 6-Fluoro-3-hydroxy-2-pyrazinecarboxamide, 6-fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide, Avigan, T-705, T705
• Formula empirica (notazione di Hill): C₅H₄FN₃O₂
• Numero CAS: 259793-96-9
• Peso molecolare: 157.10
• Numero MDL: MFCD12032148
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: certified reference material; TraceCERT^®
• Livello qualitativo: 300
• Nome Commerciale: TraceCERT^®
• Forma fisica: solid
• Durata: limited shelf life, expiry date on the label
• Produttore/marchio commerciale: Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
• applicazioni: pharmaceutical small molecule
• Temperatura di conservazione: −20°C
• Stringa SMILE: FC1=CNC(C(C(N)=O)=N1)=O
• InChI: 1S/C5H4FN3O2/c6-2-1-8-5(11)3(9-2)4(7)10/h1H,(H2,7,10)(H,8,11); ZCGNOVWYSGBHAU-UHFFFAOYSA-N

Descrizione

Descrizione generale

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com

Azioni biochim/fisiol

Favipiravir (T-705) is an inhibitor of viral RNA polymerase. In cells, the comound is converted to T-705-4-ribofuranosyl-5-triphosphate, which selectively targets the viral polymerase without affecting mammalian RNA or DNA polymerases. Favipiravir inhibits replication of inluenza viruse A, B and C with IC50 values between 0.013 and 0.48 mM. The compound protects mice from lethal-dose infections of wild type and neuraminidase inhibitor-resistant strains of H5N1 viruses, Favipiravir has been found to have activity against many viruses including flavi-, alpha-, filo-, bunya-, arena-, noro-, and of other RNA viruses, and is already used off-label for Ebola and Lassa virus.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS08
• Avvertenze: Warning
• Indicazioni di pericolo: H341,H361d
• Consigli di prudenza: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classi di pericolo: Muta. 2 - Repr. 2
• Codice della classe di stoccaggio: 4.1B - Flammable solid hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable