PHL82481

Aurapten

phyproof^® Reference Substance

• Sinonimo/i: Auraptene, 7-Geranyloxycoumarin, 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-2H-1-benzopyran-2-one, Aurapten
• Formula empirica (notazione di Hill): C₁₉H₂₂O₃
• Numero CAS: 495-02-3
• Peso molecolare: 298.38
• Numero MDL: MFCD00075948
• Codice UNSPSC: 41116107
• NACRES: NA.24

Proprietà

• Grado: primary reference standard
• Nome Commerciale: phyproof^® Reference Substance
• Saggio: ≥90.0% (HPLC)
• Forma fisica: solid
• Produttore/marchio commerciale: PhytoLab
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: C\C(C)=C\CC\C(C)=C\COc1ccc2C=CC(=O)Oc2c1
• InChI: 1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+; RSDDHGSKLOSQFK-RVDMUPIBSA-N

Descrizione

Descrizione generale

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Azioni biochim/fisiol

Auraptene is an estrogen receptor modulator that also acts as an ACAT inhibitor. It displays anti-tumor effects in several xenograft and chemically-induced murine tumor models. Auraptene induces apoptosis and is anti-proliferative in cancer cell lines. It has agonistic properties against PPARs, and interferes with lipid and cholesterol production by inhibiting ACAT (IC50 = 4 uM).

Note legali

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 13 - Non Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable