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Discovery® Cyano (5 µm) HPLC Columns

L × I.D. 10 cm × 3 mm, HPLC Column

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About This Item

Codice UNSPSC:
41115700
eCl@ss:
32110501
NACRES:
SB.52

product name

Colonna per HPLC Discovery® Cyano, 5 μm particle size, L × I.D. 10 cm × 3 mm

Materiali

stainless steel column

agenzia

suitable for USP L10

Nome Commerciale

Discovery®

Caratteristiche

endcapped

Produttore/marchio commerciale

Discovery®

Confezionamento

1 ea of

Grado di funzionalizzazione

4.5% Carbon loading

Parametri

≤70 °C temp. range
400 bar pressure (5801 psi)

tecniche

HPLC: suitable
LC/MS: suitable

Lungh. × D.I.

10 cm × 3 mm

Area superficiale

200 m2/g

Copertura della superficie

3.5 μmol/m2

Impurezze

<10 ppm metals

Matrice

silica gel, high purity, spherical base material
fully porous particle

Gruppo funzionale matrice

cyano phase

Dimensione particelle

5 μm

Dimensione pori

180 Å

operating pH range

2-8

applicazioni

food and beverages

Tecnica di separazione

hydrophilic interaction (HILIC)
normal phase
reversed phase

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Caratteristiche e vantaggi

  • Bassa idrofobia per una rapida eluizione degli analiti idrofobi
  • Forma di picco e ritenzione di analiti fortemente basici eccellenti
  • Ritenzione di analiti polari
  • Selettività unica
  • Ritenzione significativamente minore rispetto al C18 (di solito necessita di una percentuale inferiore di fase mobile organica)
  • Separazioni LC-MS stabili e a basso bleeding.
  • Compatibile con fasi organiche molto acquose

Prodotti consigliati

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Note legali

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany

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Certificati d'analisi (COA)

Lot/Batch Number
283703-01
269219-01
158453-01
153563-02
153563-01

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E F Nemeth et al.
The Journal of pharmacology and experimental therapeutics, 299(1), 323-331 (2001-09-19)
Despite the discovery of many ions and molecules that activate the Ca2+ receptor, there are no known ligands that block this receptor. Reported here are the pharmacodynamic properties of a small molecule, NPS 2143, which acts as an antagonist at
Aaron D Milstein et al.
Trends in pharmacological sciences, 29(7), 333-339 (2008-06-03)
Presynaptic glutamate release elicits brief waves of membrane depolarization in neurons by activating AMPA receptors. Depending on its precise size and shape, current through AMPA receptors gates downstream processes like NMDA receptor activation and action potential generation. Over a decade
Aleem Gangjee et al.
Journal of medicinal chemistry, 53(22), 8116-8128 (2010-10-27)
Two classes of molecules were designed and synthesized based on a 6-CH(3) cyclopenta[d]pyrimidine scaffold and a pyrrolo[2,3-d]pyrimidine scaffold. The pyrrolo[2,3-d]pyrimidines were synthesized by reacting ethyl 2-cyano-4,4-diethoxybutanoate and acetamidine, which in turn was chlorinated and reacted with the appropriate anilines to
Xuqing Zhang et al.
Journal of medicinal chemistry, 50(16), 3857-3869 (2007-07-20)
A novel series of pyrazolines 2 have been designed, synthesized, and evaluated by in vivo screening as tissue-selective androgen receptor modulators (SARMs). Structure-activity relationships (SAR) were investigated at the R1 to R6 positions as well as the core pyrazoline ring
Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
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