SRP8028

DR6 (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Sinonimo/i: CD358, TNFRSF21, Tumor necrosis factor receptor superfamily member 21
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Origine biologica: human
• Ricombinante: expressed in HEK 293 cells
• Saggio: >95% (SDS-PAGE)
• Stato: lyophilized
• PM: ~80 kDa by SDS-PAGE
• Confezionamento: pkg of 50 μg
• Condizioni di stoccaggio: avoid repeated freeze/thaw cycles
• Impurezze: <0.1 EU/μg endotoxin, tested
• Colore: white
• N° accesso UniProt: O75509
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... TNFRSF21(27242)

Descrizione

Descrizione generale

DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.

Stato fisico

Lyophilized from PBS.

Ricostituzione

Reconstitute with 50 μL deionized water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.

Altre note

The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable