SRP6113
UGDH human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Sinonimo/i:
GDH, UDP-GlcDH, UDP-glucose dehydrogenase, UDPGDH, UGD
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About This Item
Prodotti consigliati
Origine biologica
human
Ricombinante
expressed in E. coli
Saggio
≥95% (SDS-PAGE)
Forma fisica
liquid
PM
59.5 kDa (533 aa, 1-494 aa + NT His-Tag)
Confezionamento
pkg of 50 μg
N° accesso NCBI
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
Informazioni sul gene
human ... UGDH(7358)
Descrizione generale
UDP-glucose 6-dehydrogenase (UGDH) is encoded by the gene mapped to human chromosome 4p14. UGDH is part of the UDP-glucose/GDP-mannose dehydrogenase family and is a widely expressed enzyme localized in the liver.
Azioni biochim/fisiol
UDP-glucose 6-dehydrogenase (UGDH) transfers UDP-glucose to UDP-glucuronate and thus takes part in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. UGDH is implicated in various cellular processes such as, detoxification, polysaccharide biosynthesis and embryonic development.
Stato fisico
0.5 mg/mL solution in 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1 mM DTT, 0.1 M NaCl, and 1 mM EDTA.
Nota sulla preparazione
Centrifuge the vial prior to opening.
Altre note
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSELEM FEIKKICCIG AGYVGGPTCS VIAHMCPEIR VTVVDVNESR INAWNSPTLP IYEPGLKEVV ESCRGKNLFF STNIDDAIKE ADLVFISVNT PTKTYGMGKG RAADLKYIEA CARRIVQNSN GYKIVTEKST VPVRAAESIR RIFDANTKPN LNLQVLSNPE FLAEGTAIKD LKNPDRVLIG GDETPEGQRA VQALCAVYEH WVPREKILTT NTWSSELSKL AANAFLAQRI SSINSISALC EATGADVEEV ATAIGMDQRI GNKFLKASVG FGGSCFQKDV LNLVYLCEAL NLPEVARYWQ QVIDMNDYQR RRFASRIIDS LFNTVTDKKI AILGFAFKKD TGDTRESSSI YISKYLMDEG AHLHIYDPKV PREQIVVDLS HPGVSEDDQV SRLVTISKDP YEACDGAHAV VICTEWDMFK ELDYERIHKK MLKPAFIFDG RRVLDGLHNE LQTIGFQIET IGKKVSSKRI PYAPSGEIPK FSLQDPPNKK PKV
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Ping Cai et al.
Bioscience, biotechnology, and biochemistry, 79(7), 1090-1093 (2015-03-15)
An NADPH-dependent sorbose reductase from Candida albicans was identified to catalyze the asymmetric reduction of ethyl 4-chloro-3-oxobutanoate (COBE). The activity of the recombinant enzyme toward COBE was 6.2 U/mg. The asymmetric reduction of COBE was performed with two coexisting recombinant
Assignment1 of the UGDH locus encoding UDP-glucose dehydrogenase to human chromosome band 4p15. 1 by radiation hybrid mapping.
Marcu O, et al.
Cytogenetic and genome research, 86(3-4), 244-245 (1999)
UDP-glucose dehydrogenase activity and optimal downstream cellular function require dynamic reorganization at the dimer-dimer subunit interfaces.
Hyde A S, et al.
The Journal of Biological Chemistry, M113-M113 (2013)
cDNA cloning and expression analysis of the human UDPglucose dehydrogenase.
Peng H L, et al.
Proceedings of the National Science Council, Republic of China. Part B, Life Sciences, 22(4), 166-172 (1998)
Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer.
Tada M, et al.
Cancer Science, 101(5), 1261-1269 (2010)
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