SRP6081
TXNRD1 human
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
Sinonimo/i:
GRIM-12, MGC9145, TR1, TRXR1, Thioredoxin reductase
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About This Item
Prodotti consigliati
Origine biologica
human
Ricombinante
expressed in E. coli
Saggio
≥95% (SDS-PAGE)
Forma fisica
liquid
Potenza
0.48 units/mL
PM
55.7 kDa
Confezionamento
pkg of 100 μg
N° accesso NCBI
Condizioni di spedizione
dry ice
Temperatura di conservazione
−70°C
Informazioni sul gene
human ... TXNRD1(7296)
Descrizione generale
Thioredoxin reductase 1 (TNXRD1), cytoplasmic is an enzyme in humans that is encoded by the TXNRD1 gene. This gene encodes a member of the family of pyridine nucleotide oxidoreductases and is localized on human chromosome 12.
Azioni biochim/fisiol
Thioredoxin reductase 1 (TNXRD1) reduces thioredoxins as well as other substrates. It plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses flavin adenine dinucleotide (FAD) as a cofactor. Inhibition of TXNRD1 activity may provide for potential treatments of cancer, acquired immune deficiency syndrome (AIDS), autoimmune diseases as well as bacterial infections and parasitic diseases.
Stato fisico
0.5 mg/mL solution in PBS (pH 7.4) containing 20% glycerol.
Nota sulla preparazione
Centrifuge the vial prior to opening.
Altre note
MGSSHHHHHH SSGLVPRGSH MYDYDLIIIG GGSGGLAAAK EAAQYGKKVM VLDFVTPTPL GTRWGLGGTC VNVGCIPKKL MHQAALLGQA LQDSRNYGWK VEETVKHDWD RMIEAVQNHI GSLNWGYRVA LREKKVVYEN AYGQFIGPHR IKATNNKGKE KIYSAERFLI ATGERPRYLG IPGDKEYCIS SDDLFSLPYC PGKTLVVGAS YVALECAGFL AGIGLDVTVM VRSILLRGFD QDMANKIGEH MEEHGIKFIR QFVPIKVEQI EAGTPGRLRV VAQSTNSEEI IEGEYNTVML AIGRDACTRK IGLETVGVKI NEKTGKIPVT DEEQTNVPYI YAIGDILEDK VELTPVAIQA GRLLAQRLYA GSTVKCDYEN VPTTVFTPLE YGACGLSEEK AVEKFGEENI EVYHSYFWPL EWTIPSRDNN KCYAKIICNT KDNERVVGFH VLGPNAGEVT QGFAAALKCG LTKKQLDSTI GIHPVCAEVF TTLSVTKRSG ASILQAGC
Codice della classe di stoccaggio
13 - Non Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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