SRP4304

NGF-beta from mouse

recombinant, expressed in E. coli, ≥98% (SDS-PAGE)

• Sinonimo/i: Nerve Growth Factor β, Ngf, Ngfb
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Origine biologica: mouse
• Ricombinante: expressed in E. coli
• Saggio: ≥98% (SDS-PAGE)
• Stato: lyophilized
• Potenza: 0.2 ng/mL ED₅₀
• PM: ~13.4 kDa
• Confezionamento: pkg of 20 μg
• Impurezze: endotoxin, tested
• N° accesso NCBI: P01139
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• Informazioni sul gene: mouse ... Ngf(18049)

Descrizione

Descrizione generale

Nerve growth factor-β (NGF-β) belongs to the neurotrophin family. The active form of human NGF-β is a homodimer, non-glycosylated chain.

Azioni biochim/fisiol

Nerve growth factor-β (NGF-β) is a potent neurotrophic factor that supports the growth and survivability of nerve and/or glial cells. It brings pro-survival effects with the help of receptor tyrosine kinase TrkA. NGF-β is associated with diabetic neuropathy and ischemic heart disease. It is also involved in airway nerve system. NGF-β is also responsible for the pain which is linked with osteoarthritis (OA). It is involved in liver fibrosis, carcinogenesis, angiogenesis and cholangiocyte proliferation.

Stato fisico

Lyophilized without any additives.

Ricostituzione

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL containing 1% HSA or BSA. The solution can be diluted into other aqueous buffers and stored at 4°C for 2-7 days or store at –20°C for future use.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable