SML0500

GSK334429 hydrochloride

≥98% (HPLC)

• Sinonimo/i: 1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride
• Formula empirica (notazione di Hill): C₂₀H₂₉F₃N₄O · xHCl
• Numero CAS: 799558-94-4
• Peso molecolare: 398.47 (free base basis)
• Numero MDL: MFCD22666404
• Codice UNSPSC: 12352200
• ID PubChem: 329825449
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Stato: powder
• Condizioni di stoccaggio: desiccated
• Colore: white to beige
• Solubilità: H₂O: 5 mg/mL (clear solution)
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
• InChI: 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H; RCZVWLOXPFGZDD-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

GSK334429 is a selective histamine H3 receptor antagonist.

GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.

Caratteristiche e vantaggi

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Altre note

Store desiccated; dry room.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable