SCP0159
Granzyme B Substrate / Caspase 3 Processing Enzyme Substrate / Caspase 8 Processing Enzyme Substrate
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About This Item
Prodotti consigliati
Saggio
≥95% (HPLC)
Forma fisica
lyophilized
Composizione
Peptide Content, ≥85%
Condizioni di stoccaggio
protect from light
Temperatura di conservazione
−20°C
Amino Acid Sequence
Z-Ile-Glu-Thr-Asp-pNA
Applicazioni
Caspase 8 Processing Enzyme Substrate (Z-Ile-Glu-Thr-Asp-pNA; zIETD-pNa) is used as a substrate to identify, differentiate and characterize Granzyme B, Caspase 3 Processing Enzyme(s) and Caspase 8 Processing enzyme(s). Z-Ile-Glu-Thr-Asp-pNA is closely related to Z-Ile-Glu-Thr-Asp-fluoromethylketone (zIETD-fmk), an inhibitor of Caspase 8.
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.
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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Journal of leukocyte biology, 75(6), 1045-1055 (2004-04-13)
Caspases are key molecules in the control of apoptosis, but relatively little is known about their contribution to eosinophil apoptosis. We examined caspase-3, -8, and -9 activities in receptor ligation-dependent apoptosis induction in the differentiated human eosinophilic cell line EoL-1.
The Journal of biological chemistry, 279(35), 37201-37207 (2004-06-19)
Mast cells play an important role in both allergy and innate immunity. Recently, we demonstrated an active interaction between human mast cells and Pseudomonas aeruginosa leading to the production of multiple cytokines. Here, we show that both primary cultured human
Journal of immunology (Baltimore, Md. : 1950), 165(10), 5612-5620 (2000-11-09)
Past studies have shown that TNF-related apoptosis-inducing ligand (TRAIL) induced apoptosis in a high proportion of cultured melanoma by caspase-dependent mechanisms. In the present studies we have examined whether TRAIL-induced apoptosis of melanoma was mediated by direct activation of effector
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