This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with mental retardation. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Immunogeno
A synthetic peptide corresponding to a sequence within amino acids 70-150 of human RAIDD/CRADD (P78560).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Applicazioni
WB, IHC
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
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Certificati d'analisi (COA)
Lot/Batch Number
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