SAB5600038
Anti-Gamma H2AX (phospho-Ser139) antibody, Rabbit monoclonal
recombinant, expressed in HEK 293 cells, clone RM224, purified immunoglobulin
Sinonimo/i:
H2AX Ser139 p, Histone H2AX (phospho ser139)
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About This Item
Codice UNSPSC:
12352203
NACRES:
NA.41
Prodotti consigliati
Ricombinante
expressed in HEK 293 cells
Livello qualitativo
Forma dell’anticorpo
purified immunoglobulin
Tipo di anticorpo
primary antibodies
Clone
RM224, monoclonal
recombinant monoclonal
Forma fisica
buffered aqueous glycerol solution
Reattività contro le specie
human
Concentrazione
~1 mg/mL
tecniche
ELISA: 0.2- 1 μg/mL
immunoblotting: 0.5-2 μg/mL
immunocytochemistry: 0.5-2 μg/mL
Isotipo
IgG
N° accesso NCBI
Condizioni di spedizione
wet ice
Temperatura di conservazione
−20°C
modifica post-traduzionali bersaglio
phosphorylation (pSer139)
Informazioni sul gene
human ... H2AX(3014)
Descrizione generale
Histone H2AX (H2A histone family member X), a histone variant present in almost all eukaryotes, is coded by H2AFX gene. It is mapped to human chromosome 11q23.2–11q23.3.
Specificità
This antibody reacts to Histone H2A.X only when phosphorylated at serine 139. No cross reactivity with other phosphorylated histones.
Immunogeno
Synthetic peptide corresponding to Phospho-Histone H2AX (Ser139)
Azioni biochim/fisiol
H2AX (H2A histone family member X) helps to maintain genome stability. It plays an important role in localisation and structuring of the repair focus. H2AX also plays an active role in supplying the active repair proteins. γH2AX participates in DSB repair. This protein serves as a signal and target of phosphorylation in the spreading phase.
Caratteristiche e vantaggi
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Stato fisico
Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 2
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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