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RAB0711

Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit

Name: Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit
Brand: SIGMA

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Informazioni su questo articolo

NACRES:

NA.84

UNSPSC Code:

41116158

Gene information:

human ... CSF1R(1436)

Species reactivity:

human

Storage temp.:

−20°C

Shipped in:

wet ice

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Proprietà

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CSF1R(1436)

Descrizione

General description

CSF1R (colony stimulating factor 1 receptor) is a member of the platelet-derived growth factor (PDGF) family of proteins and is a type III RTK (receptor tyrosine kinase). CSF1R is composed of five immunoglobulin (Ig)-like domains, a transmembrane region, a juxtamembrane domain and kinase insert domain (KID) intersecting the kinase domain.

The antibody pair provided in this kit recognizes human Macrophage Colony-stimulating Factor 1 Receptor.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

CSF1R (colony stimulating factor 1 receptor) acts as a receptor for CSF1 and regulates monocyte and macrophage functioning. The protein and its ligand are linked to poor prognosis in patients with solid tumors and in patients with female reproductive cancers. In breast cancers, with decreased claudin levels, this protein regulates the switch between proliferative and invasive state of the tumor, acting downstream of TGFβ (tumor growth factor β). Haploinsufficiency in this receptor might lead to aberration of microglial function, which might be a contributor to the pathogenesis of hereditary diffuse leukoencephalopathy with spheroids (HDLS).

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Questo articolo	RAB0665	RAB0098	RAB0680
Sigma-Aldrich RAB0711 Human CSF1R / Macrophage Colony-stimulating Factor 1 Receptor ELISA Kit	Sigma-Aldrich RAB0665 Human CSF3R / Granulocyte Colony-Stimulating Factor Receptor ELISA Kit	Sigma-Aldrich RAB0098 Human M-CSF / CSF1 ELISA Kit	Sigma-Aldrich RAB0680 Human IGF2R / Cation-independent mannose-6-phosphate Receptor ELISA Kit
description -	description -	description for serum, plasma, cell culture supernatant, urine	description -
species reactivity human	species reactivity human	species reactivity human	species reactivity human
Gene Information human ... CSF1R(1436)	Gene Information human ... CSF3R(1441)	Gene Information human ... CSF1(1435)	Gene Information human ... IGF2R(3482)
assay range inter-assay cv: <10% intra-assay cv: <12%	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.1 ng/mL standard curve range: 0.102-25 ng/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 5 pg/mL standard curve range: 2.78-2000 pg/mL	assay range inter-assay cv: <12% intra-assay cv: <10% sensitivity: 0.27 ng/mL standard curve range: 0.274-200 ng/mL
technique(s) ELISA: suitable	technique(s) ELISA: suitable	technique(s) ELISA: suitable, capture ELISA: suitable	technique(s) ELISA: suitable
detection method colorimetric	detection method colorimetric	detection method colorimetric	detection method colorimetric
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C

I componenti del kit sono disponibili anche separatamente

N° Catalogo

Descrizione

SDS & Determinazione del prezzo

RABTMB3
ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
SDS

RABSTOP3
ELISA Stop Solution (Item I)
SDS

RABWASH4
20X Wash Buffer (Item B)
SDS

Pittogrammi

GHS05

Parola di avvertenza

Warning

Codici di pericolo

H290

Avvertenze di sicurezza

P234 - P390

Hazard Classifications

Met. Corr. 1

Punto di infiammabilità (°F)

Not applicable

Punto di infiammabilità (°C)

Not applicable

Classe di stoccaggio

10 - Combustible liquids

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Lot/Batch Number

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