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RAB0220

Sigma-Aldrich

Mouse ICAM-1 ELISA Kit

for serum, plasma and cell culture supernatant

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About This Item

Codice UNSPSC:
41116158
NACRES:
NA.32

Reattività contro le specie

mouse

Confezionamento

kit of 96 wells (12 strips x 8 wells)

tecniche

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 24.69-6000 pg/mL

Metodo di rivelazione

colorimetric

Condizioni di spedizione

wet ice

Temperatura di conservazione

−20°C

Informazioni sul gene

mouse ... Icam1(15894)

Descrizione generale

The Mouse ICAM-1 (Intercellular Adhesion Molecule-1) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of mouse ICAM-1 in serum, plasma, cell culture supernatants and urine.

Immunogeno

Recombinant Mouse ICAM1

Applicazioni

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Azioni biochim/fisiol

Intercellular adhesion molecule-1 (ICAM-1) is a member of immunoglobulin (Ig) superfamily. It is an inducible transmembrane glycoprotein. ICAM-1 mediates adhesion of circulating leukocytes to the endothelial membrane and blood vessel. ICAM-1 might cause atherosclerosis and the polymorphism in ICAM-1 has reduced risk to cardiovascular diseases. IL-6 induces the upregulation of ICAM-1 and leads to metastasis of osteosarcoma cells. ICAM-1 causes invasion and metastasis of breast cancer cells. ICAM-1 is an important receptor for rhinovirus and Haemophilus influenzae binding. Upregulation of ICAM-1 in the respiratory tract of chronic airway limitation patients increases the risk of respiratory infections.

Altre note

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

I componenti del kit sono disponibili anche separatamente

N° Catalogo
Descrizione
SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABELADDELISA 5X Assay/Sample Diluent Buffer D (Item K)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pittogrammi

Corrosion
GHS05

Avvertenze

Warning

Indicazioni di pericolo

H290

Consigli di prudenza

P234 - P390

Classi di pericolo

Met. Corr. 1

Codice della classe di stoccaggio

8A - Combustible corrosive hazardous materials

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease
Liu A, et al.
Medicine, 97(40), e12523-e12523 (2018)
The main rhinovirus respiratory tract adhesion site (ICAM-1) is upregulated in smokers and patients with chronic airflow limitation (CAL)
Shukla SD, et al.
Respiratory Research, 18(1), 6-6 (2017)
Role of ICAM1 in invasion of human breast cancer cells
Rosette C, et al.
Carcinogenesis, 26(5), 943-950 (2005)
IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
Lin YM, et al.
Cancer Letters, 328(1), 135-143 (2013)
Jochen G Schneider et al.
International journal of cardiology, 176(1), 139-144 (2014-08-03)
Coagulation and prothrombotic potential have genuinely been associated with increased cardiovascular risk. However, not all studies in this regard are conclusive. Some clinical trials have shown an increased frequency of cardiovascular complications in patients receiving direct thrombin inhibitors. Previous data
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